Literature DB >> 7709104

[Extravasation of paclitaxel (Taxol)].

E Raymond1, S Cartier, C Canuel, C Louvet, B Demuynck, M Debray, C Varette, S Baux, M Mimoun, A de Gramont.   

Abstract

Paclitaxel is a new antimitotic derived from yew-tree, used for the treatment of ovarian and breast cancers. The local toxicity of paclitaxel is still poorly known. We report one of the first observations of accidental subcutaneous extravastion of paclitaxel. Local epidermic necrosis was observed and evolution was good with local treatment only. Treatments of such extravasation are discussed.

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Year:  1995        PMID: 7709104     DOI: 10.1016/0248-8663(96)80679-5

Source DB:  PubMed          Journal:  Rev Med Interne        ISSN: 0248-8663            Impact factor:   0.728


  2 in total

Review 1.  Extravasation of chemotherapy.

Authors:  Seppo W Langer
Journal:  Curr Oncol Rep       Date:  2010-07       Impact factor: 5.075

Review 2.  A review of clinical experience with paclitaxel extravasations.

Authors:  Brad L Stanford; Fred Hardwicke
Journal:  Support Care Cancer       Date:  2003-03-27       Impact factor: 3.603

  2 in total

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