| Literature DB >> 7706784 |
M Altamirano1, A Delaney, A Wong, J Marostenmaki, D Pi.
Abstract
The distribution pattern of hepatitis C virus (HCV) genotypes among patients from British Columbia has been investigated by reverse transcription polymerase chain reaction (PCR) amplification of the 5' noncoding region (NCR) and direct DNA sequencing of the PCR product. The sequence data obtained from the British Columbia isolates were compared with HCV sequences for the NCR obtained from GenBank for the construction of a phylogenetic tree using the GDE program, version 2.2. The data show that in British Columbia there are 7 subtypes distributed among major genotypes 1, 2, and 3. The study also shows a new subtype of genotype 1 that represents 29% of the analyzed cases.Entities:
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Year: 1995 PMID: 7706784 DOI: 10.1093/infdis/171.4.1034
Source DB: PubMed Journal: J Infect Dis ISSN: 0022-1899 Impact factor: 5.226