Literature DB >> 7706135

Mer-A2026A and B, novel piericidins with vasodilating effect. I. Producing organism, fermentation, isolation and biological properties.

K Kominato1, Y Watanabe, S Hirano, T Kioka, T Terasawa, T Yoshioka, K Okamura, H Tone.   

Abstract

A strain of Streptomyces was found to produce new piericidins. The compounds were purified and separated into two substances named Mer-A2026A and B. These new piericidins exhibited vasodilating and depressor activities.

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Year:  1995        PMID： 7706135     DOI： 10.7164/antibiotics.48.99

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  5 in total

1.  Evolutionary stability of antibiotic protection in a defensive symbiosis.

Authors:  Tobias Engl; Johannes Kroiss; Marco Kai; Taras Y Nechitaylo; Aleš Svatoš; Martin Kaltenpoth
Journal:  Proc Natl Acad Sci U S A       Date:  2018-02-14       Impact factor: 11.205

Review 2.  The unique chemistry and biology of the piericidins.

Authors:  Xuefeng Zhou; William Fenical
Journal:  J Antibiot (Tokyo)       Date:  2016-06-15       Impact factor: 2.649

3.  An NF-κB-based high-throughput screen identifies piericidins as inhibitors of the Yersinia pseudotuberculosis type III secretion system.

Authors:  Miles C Duncan; Weng Ruh Wong; Allison J Dupzyk; Walter M Bray; Roger G Linington; Victoria Auerbuch
Journal:  Antimicrob Agents Chemother       Date:  2013-12-02       Impact factor: 5.191

4.  Modulation of Specialized Metabolite Production in Genetically Engineered Streptomyces pactum.

Authors:  Zhiran Ju; Wei Zhou; Hattan A Alharbi; Daniel C Howell; Taifo Mahmud
Journal:  ACS Chem Biol       Date:  2021-11-01       Impact factor: 5.100

5.  Antifungal compounds from Streptomyces associated with attine ants also inhibit Leishmania donovani.

Authors:  Humberto E Ortega; Leonardo L G Ferreira; Weilan G P Melo; Ana Ligia L Oliveira; René F Ramos Alvarenga; Norberto P Lopes; Tim S Bugni; Adriano D Andricopulo; Mônica T Pupo
Journal:  PLoS Negl Trop Dis       Date:  2019-08-05
  5 in total

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