| Literature DB >> 7706124 |
Y Cai1, A Fredenhagen, P Hug, H H Peter.
Abstract
From the staurosporine-producing strain Streptomyces longisporoflavus R-19 various minor metabolites were isolated: They include a new compound with a nitro function in C-4' and other metabolites related to staurosporine. The new structures were elucidated by spectroscopic methods, mainly 1H NMR and 13C NMR and by comparison with TAN-1030A. The new compounds inhibited protein kinase C with IC50 values in the nanomolar range.Entities:
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Year: 1995 PMID： 7706124 DOI： 10.7164/antibiotics.48.143
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649