Literature DB >> 7705845

A high-density microsatellite map of the ataxia-telangiectasia locus.

L Vanagaite1, M R James, G Rotman, K Savitsky, A Bar-Shira, S Gilad, Y Ziv, V Uchenik, A Sartiel, F S Collins, V C Sheffield, C W Richard, J Weissenbach, Y Shiloh.   

Abstract

The locus of the autosomal recessive disorder ataxia-telangiectasia (A-T) has been assigned by linkage analysis with biallelic markers to a 4-Mb interval on chromosome 11q22-23, between GRIA4 and D11S1897. We have undertaken to saturate the A-T region with highly polymorphic microsatellite markers. To this end, we have identified seven new polymorphic CA-repeats in this region, and have mapped to it five new markers generated by Genethon and the Cooperative Human Linkage Center. These markers are in addition to 12 others that we have previously mapped or generated at the A-T locus. All 24 markers have been integrated into a high-density microsatellite map spanning some 6 Mb DNA. This map, which contains the A-T locus and flanking sequences, allows the construction of extensive, highly informative haplotypes.

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Year:  1995        PMID： 7705845     DOI： 10.1007/BF00208975

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  12 in total

1.  Localization of an ataxia-telangiectasia locus to a 3-cM interval on chromosome 11q23: linkage analysis of 111 families by an international consortium.

Authors:  T Foroud; S Wei; Y Ziv; E Sobel; E Lange; A Chao; T Goradia; Y Huo; A Tolun; L Chessa; P Charmley; O Sanal; N Salman; C Julier; P Concannon; C McConville; A M Taylor; Y Shiloh; S K Lange; R A Gatti
Journal:  Am J Hum Genet       Date:  1991-12       Impact factor: 11.025

2.  A radiation hybrid map of 506 STS markers spanning human chromosome 11.

Authors:  M R James; C W Richard; J J Schott; C Yousry; K Clark; J Bell; J D Terwilliger; J Hazan; C Dubay; A Vignal
Journal:  Nat Genet       Date:  1994-09       Impact factor: 38.330

3.  The ATC (ataxia-telangiectasia complementation group C) locus localizes to 11q22-q23.

Authors:  Y Ziv; G Rotman; M Frydman; J Dagan; T Cohen; T Foroud; R A Gatti; Y Shiloh
Journal:  Genomics       Date:  1991-02       Impact factor: 5.736

4.  A YAC contig spanning the ataxia-telangiectasia locus (groups A and C) at 11q22-q23.

Authors:  G Rotman; K Savitsky; Y Ziv; C G Cole; M J Higgins; I Bar-Am; I Dunham; A Bar-Shira; L Vanagaite; S Qin; J Zhang; N J Nowak; S C Chandrasekharappa; H Lehrach; L Avivi; T B Shows; F S Collins; D R Bentley; Y Shiloh
Journal:  Genomics       Date:  1994-11-15       Impact factor: 5.736

5.  Paired STSs amplified from radiation hybrids, and from associated YACs, identify highly polymorphic loci flanking the ataxia telangiectasia locus on chromosome 11q22-23.

Authors:  C M McConville; P J Byrd; H J Ambrose; T Stankovic; Y Ziv; A Bar-Shira; L Vanagaite; G Rotman; Y Shiloh; G T Gillett
Journal:  Hum Mol Genet       Date:  1993-07       Impact factor: 6.150

6.  Physical and genetic mapping at the ATA/ATC locus on chromosome 11q22-23.

Authors:  G Rotman; K Savitski; L Vanagaite; A Bar-Shira; Y Ziv; S Gilad; V Uchenik; S Smith; Y Shiloh
Journal:  Int J Radiat Biol       Date:  1994-12       Impact factor: 2.694

7.  A haplotype common to intermediate radiosensitivity variants of ataxia-telangiectasia in the UK.

Authors:  A M Taylor; C M McConville; G Rotman; Y Shiloh; P J Byrd
Journal:  Int J Radiat Biol       Date:  1994-12       Impact factor: 2.694

8.  Physical localization of microsatellite markers at the ataxia-telangiectasia locus at 11q22-q23.

Authors:  L Vanagaite; K Savitsky; G Rotman; Y Ziv; S C Gerken; R White; J Weissenbach; G Gillett; F J Benham; C W Richard; M R James; F S Collins; Y Shiloh
Journal:  Genomics       Date:  1994-07-01       Impact factor: 5.736

9.  A physical map across chromosome 11q22-q23 containing the major locus for ataxia telangiectasia.

Authors:  H J Ambrose; P J Byrd; C M McConville; P R Cooper; T Stankovic; J H Riley; Y Shiloh; J O McNamara; T Fukao; A M Taylor
Journal:  Genomics       Date:  1994-06       Impact factor: 5.736

10.  Localization of an ataxia-telangiectasia gene to chromosome 11q22-23.

Authors:  R A Gatti; I Berkel; E Boder; G Braedt; P Charmley; P Concannon; F Ersoy; T Foroud; N G Jaspers; K Lange
Journal:  Nature       Date:  1988-12-08       Impact factor: 49.962
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  10 in total

1.  Functional characterization and targeted correction of ATM mutations identified in Japanese patients with ataxia-telangiectasia.

Authors:  Kotoka Nakamura; Liutao Du; Rashmi Tunuguntla; Francesca Fike; Simona Cavalieri; Tomohiro Morio; Shuki Mizutani; Alfredo Brusco; Richard A Gatti
Journal:  Hum Mutat       Date:  2011-11-09       Impact factor: 4.878

2.  A locus for Fanconi anemia on 16q determined by homozygosity mapping.

Authors:  M Gschwend; O Levran; L Kruglyak; K Ranade; P C Verlander; S Shen; S Faure; J Weissenbach; C Altay; E S Lander; A D Auerbach; D Botstein
Journal:  Am J Hum Genet       Date:  1996-08       Impact factor: 11.025

3.  Localization of multiple melanoma tumor-suppressor genes on chromosome 11 by use of homozygosity mapping-of-deletions analysis.

Authors:  E K Goldberg; J M Glendening; Z Karanjawala; A Sridhar; G J Walker; N K Hayward; A J Rice; D Kurera; Y Tebha; J W Fountain
Journal:  Am J Hum Genet       Date:  2000-07-29       Impact factor: 11.025

4.  The ataxia-telangiectasia-variant genes 1 and 2 are distinct from the ataxia-telangiectasia gene on chromosome 11q23.1.

Authors:  M Stumm; R A Gatti; A Reis; N Udar; K Chrzanowska; E Seemanova; K Sperling; R D Wegner
Journal:  Am J Hum Genet       Date:  1995-10       Impact factor: 11.025

5.  ATM haplotypes and associated mutations in Iranian patients with ataxia-telangiectasia: recurring homozygosity without a founder haplotype.

Authors:  Mahnoush Babaei; Midori Mitui; Eric R Olson; Richard A Gatti
Journal:  Hum Genet       Date:  2005-04-21       Impact factor: 4.132

6.  Ataxia-telangiectasia: identification and detection of founder-effect mutations in the ATM gene in ethnic populations.

Authors:  M Telatar; S Teraoka; Z Wang; H H Chun; T Liang; S Castellvi-Bel; N Udar; A L Borresen-Dale; L Chessa; E Bernatowska-Matuszkiewicz; O Porras; M Watanabe; A Junker; P Concannon; R A Gatti
Journal:  Am J Hum Genet       Date:  1998-01       Impact factor: 11.025

7.  Autosomal recessive spinocerebellar ataxia and peripheral neuropathy with raised alpha-fetoprotein.

Authors:  Louise Izatt; Andrea H Németh; Anjela Meesaq; Kerry R Mills; A Malcolm R Taylor; Christopher E Shaw
Journal:  J Neurol       Date:  2004-07       Impact factor: 4.849

8.  ATM variants 7271T>G and IVS10-6T>G among women with unilateral and bilateral breast cancer.

Authors:  J L Bernstein; L Bernstein; W D Thompson; C F Lynch; K E Malone; S L Teitelbaum; J H Olsen; H Anton-Culver; J D Boice; B S Rosenstein; A-L Børresen-Dale; R A Gatti; P Concannon; R W Haile
Journal:  Br J Cancer       Date:  2003-10-20       Impact factor: 7.640

9.  A-TWinnipeg: Pathogenesis of rare ATM missense mutation c.6200C>A with decreased protein expression and downstream signaling, early-onset dystonia, cancer, and life-threatening radiotoxicity.

Authors:  Kotoka Nakamura; Francesca Fike; Sara Haghayegh; Rachel Saunders-Pullman; Angelika J Dawson; Thilo Dörk; Richard A Gatti
Journal:  Mol Genet Genomic Med       Date:  2014-03-13       Impact factor: 2.183

10.  Diabetes in Patients With Ataxia Telangiectasia: A National Cohort Study.

Authors:  Helena Donath; Ursula Hess; Matthias Kieslich; Marius Theis; Ute Ohlenschläger; Ralf Schubert; Sandra Woelke; Stefan Zielen
Journal:  Front Pediatr       Date:  2020-07-09       Impact factor: 3.418
  10 in total

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