Literature DB >> 7703904

Ascorbic acid is cytotoxic for pediatric tumor cells cultured in vitro.

M A Medina1, R García de Veas, L Schweigerer.   

Abstract

2 mM Ascorbic acid has a potent cytotoxic effect on neuroblastoma, osteosarcoma, retinoblastoma, and rhabdomyosarcoma cells cultured in vitro. At a lower concentration (0.2 mM), ascorbic acid remains highly cytotoxic for neuroblastoma, osteosarcoma and retinoblastoma cells, but it has a stimulatory effect on the growth of rhabdomyosarcoma cells.

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Year:  1994        PMID： 7703904

Source DB:  PubMed          Journal:  Biochem Mol Biol Int        ISSN： 1039-9712


  4 in total

1.  Antiproliferative and apoptotic effect of ascorbyl stearate in human glioblastoma multiforme cells: modulation of insulin-like growth factor-I receptor (IGF-IR) expression.

Authors:  K A Naidu; J L Tang; K A Naidu; L D Prockop; S V Nicosia; D Coppola
Journal:  J Neurooncol       Date:  2001-08       Impact factor: 4.130

2.  Antiproliferative and proapoptotic effect of ascorbyl stearate in human pancreatic cancer cells: association with decreased expression of insulin-like growth factor 1 receptor.

Authors:  K Akhilender Naidu; Richard C Karl; Kamatham A Naidu; Domenico Coppola
Journal:  Dig Dis Sci       Date:  2003-01       Impact factor: 3.199

3.  Vitamin C in human health and disease is still a mystery? An overview.

Authors:  K Akhilender Naidu
Journal:  Nutr J       Date:  2003-08-21       Impact factor: 3.271

4.  Antineoplastic activity of a nutrient mixture in Y-79 malignant retinoblastoma cells.

Authors:  M Waheed Roomi; Nusrath Roomi; Bilwa Bhanap; Aleksandra Niedzwiecki; Matthias Rath
Journal:  Oncol Rep       Date:  2012-10-29       Impact factor: 3.906
  4 in total

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