Literature DB >> 7703363

Metabolism and kinetics of trichloroethylene in relation to toxicity and carcinogenicity. Relevance of the mercapturic acid pathway.

A R Goeptar1, J N Commandeur, B van Ommen, P J van Bladeren, N P Vermeulen.   

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Year:  1995        PMID: 7703363     DOI: 10.1021/tx00043a001

Source DB:  PubMed          Journal:  Chem Res Toxicol        ISSN: 0893-228X            Impact factor:   3.739


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  21 in total

1.  Metabolism and tissue distribution of orally administered trichloroethylene in male and female rats: identification of glutathione- and cytochrome P-450-derived metabolites in liver, kidney, blood, and urine.

Authors:  Lawrence H Lash; David A Putt; Jean C Parker
Journal:  J Toxicol Environ Health A       Date:  2006-07

2.  Re-assessment of the influence of polymorphisms of phase-II metabolic enzymes on renal cell cancer risk of trichloroethylene-exposed workers.

Authors:  Bernd Wiesenhütter; Silvia Selinski; Klaus Golka; Thomas Brüning; Hermann M Bolt
Journal:  Int Arch Occup Environ Health       Date:  2007-05-04       Impact factor: 3.015

Review 3.  Ovarian metabolism of xenobiotics.

Authors:  Poulomi Bhattacharya; Aileen F Keating
Journal:  Exp Biol Med (Maywood)       Date:  2011-05-26

4.  The effect of trichloroethylene metabolites on the hepatic vitamin B12-dependent methionine salvage pathway and its relevance to increased excretion of formic acid in the rat.

Authors:  Noreen Yaqoob; Katarzyna M Bloch; Andrew R Evans; Edward A Lock
Journal:  Toxicol Res (Camb)       Date:  2020-04-24       Impact factor: 3.524

Review 5.  Trichloroethylene biotransformation and its role in mutagenicity, carcinogenicity and target organ toxicity.

Authors:  Lawrence H Lash; Weihsueh A Chiu; Kathryn Z Guyton; Ivan Rusyn
Journal:  Mutat Res Rev Mutat Res       Date:  2014 Oct-Dec       Impact factor: 5.657

6.  Reduction in rat oocyte fertilizability mediated by S-(1, 2-dichlorovinyl)-L-cysteine: a trichloroethylene metabolite produced by the glutathione conjugation pathway.

Authors:  Katherine Lily Wu; Trish Berger
Journal:  Bull Environ Contam Toxicol       Date:  2008-08-05       Impact factor: 2.151

7.  Preexistence of chronic tubular damage in cases of renal cell cancer after long and high exposure to trichloroethylene.

Authors:  T Brüning; K Golka; V Makropoulos; H M Bolt
Journal:  Arch Toxicol       Date:  1996       Impact factor: 5.153

8.  Alterations of the renal function in the isolated perfused rat kidney system after in vivo and in vitro application of S-(1,2-dichlorovinyl)-L-cysteine and S-(2,2-dichlorovinyl)-L-cysteine.

Authors:  O Ilinskaja; S Vamvakas
Journal:  Arch Toxicol       Date:  1996       Impact factor: 5.153

9.  Pharmacokinetic analysis of trichloroethylene metabolism in male B6C3F1 mice: Formation and disposition of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine.

Authors:  Sungkyoon Kim; David Kim; Gary M Pollack; Leonard B Collins; Ivan Rusyn
Journal:  Toxicol Appl Pharmacol       Date:  2009-05-03       Impact factor: 4.219

10.  Effects of Kombucha on oxidative stress induced nephrotoxicity in rats.

Authors:  Ola Ali Gharib
Journal:  Chin Med       Date:  2009-11-27       Impact factor: 5.455

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