Literature DB >> 7703268

[S-nitrosothiols and dinitrosothiol iron complexes as a source of nitric oxide in animals].

N V Khrapova, I V Malenkova, A F Vanin.   

Abstract

It was established by EPR method, that S-nitrosocysteine or S-nitrosohomocysteine rapid destructured with releasing nitric oxide (NO) in blood, forming with hemoglobin paramagnetic hemoglobin nitrosyl complexes (Hb-NO). In the presence of exogenous iron in blood dinitrosyl non-heme iron complexes (DNIC) with thiol-containing ligands, i.e. 2,03 complexes arose in blood. These complexes occurred in large quantity if it was introduced to animals low molecular DNIC with cysteine or homocysteine in relation iron/thiol in complexes and solution 1:20 or 1:2. 2,03 complexes in organisms was stable. So, the system of DNIC S-nitrosothiols prevailed the S-nitrosothiols conversation into DNIC.

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Year:  1995        PMID: 7703268

Source DB:  PubMed          Journal:  Biofizika        ISSN: 0006-3029


  2 in total

1.  Complexes of iron(II) with cysteine-containing peptides in the gas phase.

Authors:  O V Nemirovskiy; M L Gross
Journal:  J Am Soc Mass Spectrom       Date:  1996-09       Impact factor: 3.109

2.  Gas phase studies of the interactions of Fe2+ with cysteine-containing peptides.

Authors:  O V Nemirovskiy; M L Gross
Journal:  J Am Soc Mass Spectrom       Date:  1998-12       Impact factor: 3.109

  2 in total

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