Literature DB >> 7702627

Antioxidant function of recombinant human natural killer enhancing factor.

H Sauri1, L Butterfield, A Kim, H Shau.   

Abstract

Natural killer enhancing factor (NKEF) is a member of a new class of highly conserved antioxidant proteins. Members of this family have been described as thiol-specific antioxidants. In this study, we show that recombinant proteins encoded by the two human NKEF genes (nkef-A and B) possess antioxidant function in the protection of protein and DNA from oxidative damage. The production of separate proteins from each of the genes encoding NKEF is an important step in the elucidation of its function.

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Year:  1995        PMID： 7702627     DOI： 10.1006/bbrc.1995.1428

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  18 in total

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Journal:  Proc Natl Acad Sci U S A       Date:  2004-11-30       Impact factor: 11.205

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Journal:  Results Immunol       Date:  2011-08-26

3.  Contrasting antioxidant and cytotoxic effects of peroxiredoxin I and II in PC12 and NIH3T3 cells.

Authors:  S Simzar; R Ellyin; H Shau; T A Sarafian
Journal:  Neurochem Res       Date:  2000-12       Impact factor: 3.996

4.  Expression of a mitochondrial peroxiredoxin prevents programmed cell death in Leishmania donovani.

Authors:  Simone Harder; Meike Bente; Kerstin Isermann; Iris Bruchhaus
Journal:  Eukaryot Cell       Date:  2006-05

5.  Genomic organization, single nucleotide polymorphism and functional characterization of natural killer enhancing factor (NKEF-A) in Miichthys miiuy.

Authors:  Fanqiang Meng; Rixin Wang; Yunhang Gao; Tianjun Xu
Journal:  Mol Biol Rep       Date:  2013-12-19       Impact factor: 2.316

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7.  Crystal structure of a multifunctional 2-Cys peroxiredoxin heme-binding protein 23 kDa/proliferation-associated gene product.

Authors:  S Hirotsu; Y Abe; K Okada; N Nagahara; H Hori; T Nishino; T Hakoshima
Journal:  Proc Natl Acad Sci U S A       Date:  1999-10-26       Impact factor: 11.205

8.  Biochemical properties and vaccine effect of recombinant TPx-3 from Schistosoma japonicum.

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Journal:  Parasitol Res       Date:  2017-03-11       Impact factor: 2.289

9.  Plasmodium knowlesi thioredoxin peroxidase 1 binds to nucleic acids and has RNA chaperone activity.

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Journal:  Parasitol Res       Date:  2014-08-05       Impact factor: 2.289

10.  Identification and functional analysis of a novel mitochondria-localized 2-Cys peroxiredoxin, BbTPx-2, from Babesia bovis.

Authors:  Tatsunori Masatani; Masahito Asada; Hassan Hakimi; Kei Hayashi; Junya Yamagishi; Shin-Ichiro Kawazu; Xuenan Xuan
Journal:  Parasitol Res       Date:  2016-04-19       Impact factor: 2.289
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