| Literature DB >> 7701506 |
M Y Kaynar1, M Hanci, C Kuday, A Belce, K Gumustas, E Kokoglu.
Abstract
We determined time dependent changes in the levels of the antioxidant enzymes, superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT) at 1, 4 and 24 hours after standardized reversible spinal cord injury in rats. In each segment (rostral, lesion, caudal) enzyme activities at 1, 4 and 24 hours were not significantly different. Without time limitation we have found that SOD and GPx activities were not significantly different (p > 0.05), but CAT activity was significantly high (p = 0.008) in the lesion segment than the rostral and caudal segment. According to our results we suggest that one of the main reason for tissue damage during such a spinal cord trauma model may be neither H2O2 nor H2O2 derived radicals.Entities:
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Year: 1994 PMID： 7701506
Source DB: PubMed Journal: Tokushima J Exp Med ISSN： 0040-8875