Literature DB >> 7701244

Acid perception in gastro-oesophageal reflux disease is dependent on psychosocial factors.

B T Johnston1, S A Lewis, J S Collins, R J McFarland, A H Love.   

Abstract

BACKGROUND: Our aim was to contrast the psychosocial profiles of patients with gastro-oesophageal reflux disease whose symptoms correlate well with acid reflux against those whose symptoms do not.
METHODS: One hundred and one patients presenting with heartburn for the first time underwent oesophageal pH monitoring, and 82 (81%) experienced symptoms during the recording. On the basis of how well their symptoms correlated with acid reflux, patients were divided into symptom-positive and symptom-negative groups. These two groups were then compared on the basis of four questionnaires looking at different psychosocial factors.
RESULTS: Symptom-negative patients displayed significantly higher levels of trait anxiety (44.5 versus 38.7; p < 0.05) and hysteria (5.6 versus 4.1; p < 0.05). The adequacy of their social support structures was significantly lower (6.2 versus 7.3; p < 0.05). No difference in daily hassles or uplifts was found.
CONCLUSION: Significant psychosocial differences are noted in patients with poor symptom-reflux correlation. These differences may help explain the aetiology of such patients' symptoms.

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Year:  1995        PMID: 7701244     DOI: 10.3109/00365529509093228

Source DB:  PubMed          Journal:  Scand J Gastroenterol        ISSN: 0036-5521            Impact factor:   2.423


  22 in total

Review 1.  Functional heartburn: definition and management strategies.

Authors:  Frank Zerbib; Stanislas Bruley des Varannes; Mireille Simon; Jean Paul Galmiche
Journal:  Curr Gastroenterol Rep       Date:  2012-06

Review 2.  Diagnosis and Management of Functional Heartburn.

Authors:  Christine Hachem; Nicholas J Shaheen
Journal:  Am J Gastroenterol       Date:  2016-01-05       Impact factor: 10.864

3.  Hiatal hernia, lower esophageal sphincter incompetence, and effectiveness of Nissen fundoplication in the spectrum of gastroesophageal reflux disease.

Authors:  Reginald V N Lord; Steven R DeMeester; Jeffrey H Peters; Jeffrey A Hagen; Dino Elyssnia; Corinne T Sheth; Tom R DeMeester
Journal:  J Gastrointest Surg       Date:  2008-12-03       Impact factor: 3.452

Review 4.  Functional esophageal disorders.

Authors:  R E Clouse; J E Richter; R C Heading; J Janssens; J A Wilson
Journal:  Gut       Date:  1999-09       Impact factor: 23.059

Review 5.  Overlap of functional heartburn and gastroesophageal reflux disease with irritable bowel syndrome.

Authors:  Nicola de Bortoli; Irene Martinucci; Massimo Bellini; Edoardo Savarino; Vincenzo Savarino; Corrado Blandizzi; Santino Marchi
Journal:  World J Gastroenterol       Date:  2013-09-21       Impact factor: 5.742

6.  Many patients continue using proton pump inhibitors after negative results from tests for reflux disease.

Authors:  Andrew J Gawron; Jami Rothe; Angela J Fought; Anita Fareeduddin; Erin Toto; Lubomyr Boris; Peter J Kahrilas; John E Pandolfino
Journal:  Clin Gastroenterol Hepatol       Date:  2012-02-22       Impact factor: 11.382

7.  Psychological factors in gastro-oesophageal reflux disease.

Authors:  B T Johnston; S A Lewis; A H Love
Journal:  Gut       Date:  1995-04       Impact factor: 23.059

8.  Pathophysiology of functional heartburn based on Rome III criteria in Japanese patients.

Authors:  Yasuhiro Tamura; Yasushi Funaki; Shinya Izawa; Akihito Iida; Yoshiharu Yamaguchi; Kazunori Adachi; Naotaka Ogasawara; Makoto Sasaki; Hiroshi Kaneko; Kunio Kasugai
Journal:  World J Gastroenterol       Date:  2015-04-28       Impact factor: 5.742

9.  Prevalence of Psychiatric Comorbidity in Symptomatic Gastroesophageal Reflux Subgroups.

Authors:  Mustafa Melih Bilgi; Rukiye Vardar; Esra Yıldırım; Baybars Veznedaroğlu; Serhat Bor
Journal:  Dig Dis Sci       Date:  2016-08-26       Impact factor: 3.199

10.  Impaired gastric motility and its relationship to reflux symptoms in patients with nonerosive gastroesophageal reflux disease.

Authors:  Takeshi Kamiya; Hiroshi Adachi; Makoto Hirako; Michiko Shikano; Eriko Matsuhisa; Tsuneya Wada; Naotaka Ogasawara; Shunsuke Nojiri; Hiromi Kataoka; Makoto Sasaki; Hirotaka Ohara; Takashi Joh
Journal:  J Gastroenterol       Date:  2009-02-13       Impact factor: 7.527

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