OBJECTIVE: To examine the relative solubility of urate crystals in water, formalin, and ethanol. METHODS: Weighed aliquots of synthetic crystals were incubated in each solvent for 72 h at 4 degrees C and were then examined by polarized microscopy. RESULTS: urate crystals were insoluble in alcohol, sparingly soluble in water, and markedly soluble in formalin. CONCLUSION: The marked solubility of urate in formalin is consistent with formation of urate:formaldehyde addition products.
OBJECTIVE: To examine the relative solubility of urate crystals in water, formalin, and ethanol. METHODS: Weighed aliquots of synthetic crystals were incubated in each solvent for 72 h at 4 degrees C and were then examined by polarized microscopy. RESULTS:urate crystals were insoluble in alcohol, sparingly soluble in water, and markedly soluble in formalin. CONCLUSION: The marked solubility of urate in formalin is consistent with formation of urate:formaldehyde addition products.
Authors: Laurent L Reber; Philipp Starkl; Bianca Balbino; Riccardo Sibilano; Nicolas Gaudenzio; Stephan Rogalla; Steven Sensarn; Dongmin Kang; Harini Raghu; Jeremy Sokolove; William H Robinson; Christopher H Contag; Mindy Tsai; Stephen J Galli Journal: PLoS One Date: 2017-10-05 Impact factor: 3.240