K Fu1, X Ma, Z Zhang, W Chen. 1. Department of Oral and Maxillofacial Surgery, School of Stomatology, Beijing Medical University, China.
Abstract
PURPOSE: To assess tumor necrosis factor (TNF) activity in synovial fluid from patients with temporomandibular disorders. PATIENTS AND METHODS: Tumor necrosis factor (TNF) activity in synovial fluid from 27 patients with temporomandibular disorders (TMDs) was studied using the MTT tetrazolium WEHI 164 clone 13 cell cytotoxicity assay. RESULTS: No detectable TNF levels were found in five patients with a masticatory muscle disorder, but elevated TNF levels were found in 5 of 11 patients with TMJ disc displacement, and in 9 of 11 patients with degenerative joint disease. CONCLUSION: The findings of biologically active TNF in the synovial fluid of these patients suggests that it may play a role in the pathogenesis of certain temporomandibular disorders.
PURPOSE: To assess tumor necrosis factor (TNF) activity in synovial fluid from patients with temporomandibular disorders. PATIENTS AND METHODS: Tumor necrosis factor (TNF) activity in synovial fluid from 27 patients with temporomandibular disorders (TMDs) was studied using the MTT tetrazolium WEHI 164 clone 13 cell cytotoxicity assay. RESULTS: No detectable TNF levels were found in five patients with a masticatory muscle disorder, but elevated TNF levels were found in 5 of 11 patients with TMJ disc displacement, and in 9 of 11 patients with degenerative joint disease. CONCLUSION: The findings of biologically active TNF in the synovial fluid of these patients suggests that it may play a role in the pathogenesis of certain temporomandibular disorders.
Authors: Elizabeth J Bowen; Thomas W Schmidt; Christina S Firm; Andrew F Russo; Paul L Durham Journal: J Neurochem Date: 2005-11-08 Impact factor: 5.372
Authors: Abdalwhab Zwiri; Mohammad A I Al-Hatamleh; Wan Muhamad Amir W Ahmad; Jawaad Ahmed Asif; Suan Phaik Khoo; Adam Husein; Zuryati Ab-Ghani; Nur Karyatee Kassim Journal: Diagnostics (Basel) Date: 2020-05-15