Literature DB >> 7697490

A simple method for the quantitative evaluation of functional effects of xenobiotics with cultured cells.

D Lees1, D Pugnère, A Castel, O Raux, P Travo.   

Abstract

We present a simple, noninvasive, nondestructive all-purpose method for the quantitative evaluation of functional effects of xenobiotics with cultured cells and the work station for its routine, easy implementation. At present 1 to 150 cells growing in one to six dishes can be studied in parallel or otherwise at time intervals ranging from 10 s to 6 h or more, over periods of time ranging from a few tens of minutes to 3-4 days. Any aspect of cell physiological behavior can be studied (differentiation-dedifferentiation, migration, division, degeneration, death) without preliminary staining and/or fixation provided it results in optically visible changes.

Entities:  

Mesh：

Substances：

Year:  1994        PMID： 7697490     DOI： 10.1007/bf00755775

Source DB:  PubMed          Journal:  Cell Biol Toxicol        ISSN： 0742-2091            Impact factor:   6.691


  5 in total

1.  Effects of naftidrofuryl on the contraction and proliferation of cultured myocytes evoked by serotonin.

Authors:  P Bodin; P Travo
Journal:  J Cardiovasc Pharmacol       Date:  1990       Impact factor: 3.105

2.  Responses of subcultured rat aortic smooth muscle myocytes to vasoactive agents and KCl-induced depolarization.

Authors:  P Bodin; S Richard; C Travo; P Berta; J C Stoclet; S Papin; P Travo
Journal:  Am J Physiol       Date:  1991-01

3.  Quantitative method for the study of the morphological changes induced by vasoactive agents in single aortic myocytes grown in primary cultures.

Authors:  P Travo; P Bodin; G Burnstock; J C Stoclet
Journal:  Lab Invest       Date:  1987-03       Impact factor: 5.662

4.  High sensitivity of hypertensive aortic myocytes to norepinephrine and angiotensin.

Authors:  P Bodin; C Travo; J C Stoclet; P Travo
Journal:  Am J Physiol       Date:  1993-02

5.  Dystrophin (Xp21), a new phenotype marker of cultured rat aortic myocytes.

Authors:  D Lees; E Fabbrizio; D Mornet; M C Harricane; P Travo
Journal:  Exp Cell Res       Date:  1994-02       Impact factor: 3.905
  5 in total
  2 in total

1.  An hypothesis for the interpretation of the contractile response of vascular smooth muscle at the cellular level.

Authors:  P Travo; D Lees; L Benel
Journal:  Cell Biol Toxicol       Date:  1996-12       Impact factor: 6.691

Review 2.  Interest and limits of human tissue and cell use in pharmacotoxicology.

Authors:  M Potier; B Lakhdar; D Merlet; J Cambar
Journal:  Cell Biol Toxicol       Date:  1995-08       Impact factor: 6.691
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.