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Literature DB >> 769709

Persistence of antigen in nonarthritic joints.

Abstract

The presence of antigen, IgG and C3 was shown by radioautography and immunofluorescence in the collagenous tissues of the joints of animals injected intra-articularly with antigen after having been previously immunized with that antigen in Freund's incomplete adjuvant. Since these joints were shown to be virtually free of inflammatory reactions, we suggest that the persistence of immune complexes activating complement cannot fully explain the chronicity of experimental allergic arthritis.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1975 PMID： 769709 PMCID： PMC1006444 DOI： 10.1136/ard.34.5.431

Source DB: PubMed Journal: Ann Rheum Dis ISSN： 0003-4967 Impact factor: 19.103

14 in total

1. THE PREPARATION OF I-131-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY.

Authors: F C GREENWOOD; W M HUNTER; J S GLOVER
Journal: Biochem J Date: 1963-10 Impact factor: 3.857

2. The production of arthritis in rabbits by an immunological reaction to fibrin.

Authors: D C DUMONDE; L E GLYNN
Journal: Br J Exp Pathol Date: 1962-08

3. Experimental arthritis associated with auto-immunization to inflammatory exudates.

Authors: J M Phillips; P Kaklamanis; L E Glynn
Journal: Ann Rheum Dis Date: 1966-03 Impact factor: 19.103

4. Experimental arthritis, light and electron microscope studies of antigen and antibody using horseradish peroxidase as antigen.

Authors: A Doble; J Dorling; L E Glynn; J A Webb; J H Wilcox
Journal: Br J Exp Pathol Date: 1973-12

5. Production of a chronic arthritis with ovalbumin. Its retention in the rabbit knee joint.

Authors: R Consden; A Doble; L E Glynn; A P Nind
Journal: Ann Rheum Dis Date: 1971-05 Impact factor: 19.103

6. FII haemagglutination test for serum antigammaglobulin factors in arthritides sero-positive and sero-negative by other tests.

Authors: D W Zutshi; C A Reading; W V Epstein; B M Ansell; E J Holborow
Journal: Ann Rheum Dis Date: 1969-05 Impact factor: 19.103

7. Antigen retention in joint tissues in antigen-induced synovitis.

Authors: J R Hollister; M Mannik
Journal: Clin Exp Immunol Date: 1974-04 Impact factor: 4.330

8. Production of a macrophage migration inhibitory factor in rabbits with experimental arthritis.

Authors: P Stastny; T D Cooke; M Ziff
Journal: Clin Exp Immunol Date: 1973-05 Impact factor: 4.330

9. Evidence for an endogenous antigen in the adjuvant arthritic rat.

Authors: H Berry; D A Willoughby; J P Giroud
Journal: J Pathol Date: 1973-12 Impact factor: 7.996

10. The pathogenesis of chronic inflammation in experimental antigen-induced arthritis. II. Preferential localization of antigen-antibody complexes to collagenous tissues.

Authors: T D Cooke; E R Hurd; M Ziff; H E Jasin
Journal: J Exp Med Date: 1972-02-01 Impact factor: 14.307

7 in total

1. Characterisation and pharmacological sensitivity of antigen arthritis induced by methylated bovine serum albumin in the rat.

Authors: R J Griffiths
Journal: Agents Actions Date: 1992-01

2. Prolonged anti-inflammatory action of DL-lactide/glycolide copolymer nanospheres containing betamethasone sodium phosphate for an intra-articular delivery system in antigen-induced arthritic rabbit.

Authors: Eijiro Horisawa; Tsuyoshi Hirota; Satoko Kawazoe; Jun Yamada; Hiromitsu Yamamoto; Hirofumi Takeuchi; Yoshiaki Kawashima
Journal: Pharm Res Date: 2002-04 Impact factor: 4.200

3. Experimental allergic arthritis in the rabbit: alterations in the cellularity and the rate of cellular proliferation in the synovial linings of the challenged joints of rabbits immunized with antigen in Freund's incomplete adjuvant.

Authors: B Henderson; L E Glynn; J Chayen
Journal: Br J Exp Pathol Date: 1982-02

4. Pathogenic significance of serum components in the development of autoimmune polyarthritis in MRL/Mp mice bearing the lymphoproliferation gene.

Authors: J Itoh; M Nose; M Kyogoku
Journal: Am J Pathol Date: 1991-09 Impact factor: 4.307

5. Antigen handling in antigen-induced joint inflammation: kinetics of a second intra-articularly injected dose of antigen in an already established antigen-induced joint inflammation.

Authors: H J van Beusekom; L B van de Putte; W B van den Berg; W J van den Broek; W C Buijs
Journal: Immunology Date: 1981-09 Impact factor: 7.397

6. The inflammatory role of immune complexes trapped in joint collagenous tissues.

Authors: H E Jasin; T D Cooke
Journal: Clin Exp Immunol Date: 1978-09 Impact factor: 4.330

7. Is persisting antigen responsible for the chronicity of experimental allergic arthritis?

Authors: A Fox; L E Glynn
Journal: Ann Rheum Dis Date: 1977-02 Impact factor: 19.103

7 in total