Literature DB >> 7696353

cDNA cloning of a thromboxane A2 receptor from rat astrocytes.

J Kitanaka1, H Hashimoto, Y Sugimoto, M Sawada, M Negishi, A Suzumura, T Marunouchi, A Ichikawa, A Baba.   

Abstract

A cDNA clone for rat thromboxane (TX) A2 receptor was obtained from cultured astrocytes. The cDNA encodes a protein of 341 amino acids with seven putative transmembrane domains. The receptor is homologous with mouse and human TXA2 receptors at 92.7% and 71.8%, respectively. Expression of messenger RNA for the receptor was examined by reverse transcriptase-polymerase chain reaction, showing ubiquitous expression in brain glial cells such as astrocytes, oligodendrocytes and microglia.

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Year:  1995        PMID: 7696353     DOI: 10.1016/0167-4889(94)00225-4

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  7 in total

1.  Altered psychomotor behaviors in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP).

Authors:  H Hashimoto; N Shintani; K Tanaka; W Mori; M Hirose; T Matsuda; M Sakaue; J Miyazaki; H Niwa; F Tashiro; K Yamamoto; K Koga; S Tomimoto; A Kunugi; S Suetake; A Baba
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-30       Impact factor: 11.205

2.  Evidence for human thromboxane receptor heterogeneity using a novel series of 9,11-cyclic carbonate derivatives of prostaglandin F2 alpha.

Authors:  A H Krauss; D F Woodward; L L Gibson; C E Protzman; L S Williams; R M Burk; T S Gac; M B Roof; F Abbas; K Marshall; J Senior
Journal:  Br J Pharmacol       Date:  1996-03       Impact factor: 8.739

3.  Ca2+- and thromboxane-dependent distribution of MaxiK channels in cultured astrocytes: from microtubules to the plasma membrane.

Authors:  J W Ou; Y Kumar; A Alioua; C Sailer; E Stefani; L Toro
Journal:  Glia       Date:  2009-09       Impact factor: 7.452

4.  Nitric oxide-induced Cl- secretion in isolated rat colon is mediated by the release of thromboxane A2.

Authors:  Hideki Sakai; Tomoyuki Suzuki; Miki Murota; Yuji Takahashi; Noriaki Takeguchi
Journal:  J Physiol       Date:  2002-08-15       Impact factor: 5.182

5.  Thromboxane A2 Receptor Stimulation Enhances Microglial Interleukin-1β and NO Biosynthesis Mediated by the Activation of ERK Pathway.

Authors:  Wanlin Yang; Aijuan Yan; Tingting Zhang; Jiaxiang Shao; Tengyuan Liu; Xiao Yang; Weiliang Xia; Yi Fu
Journal:  Front Aging Neurosci       Date:  2016-01-29       Impact factor: 5.750

6.  Putative role of prostaglandin receptor in intracerebral hemorrhage.

Authors:  Shekher Mohan; Abdullah S Ahmad; Alexander V Glushakov; Chase Chambers; Sylvain Doré
Journal:  Front Neurol       Date:  2012-10-22       Impact factor: 4.003

7.  Thromboxane A2 receptor antagonist SQ29548 suppresses the LPS‑induced release of inflammatory cytokines in BV2 microglia cells via suppressing MAPK and NF‑κB signaling pathways.

Authors:  Aijuan Yan; Gaoyu Cai; Weiliang Xia; Yi Fu
Journal:  Mol Med Rep       Date:  2017-06-29       Impact factor: 2.952

  7 in total

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