Literature DB >> 7695322

In vivo correlates for Streptococcus pneumoniae penicillin resistance in acute otitis media.

P Gehanno1, G Lenoir, P Berche.   

Abstract

Eighty-four children suffering from acute otitis media caused by Streptococcus pneumoniae were treated prospectively with cefuroxime axetil suspension (30 mg/kg of body weight twice daily for 8 days). The high incidence of isolates with decreased susceptibilities to penicillin (42 of 84 isolates) allowed us to establish a relationship between clinical success and the penicillin MICs for pneumococcal isolates. It was found that cefuroxime axetil is clinically effective in the treatment of acute otitis media caused by penicillin-susceptible and penicillin-intermediate strains of S. pneumoniae. The results indicate that the risk of treatment failure with cefuroxime axetil was increased in children with otitis media caused by S. pneumoniae when the penicillin MIC were greater than or equal to 2 mg/liter.

Entities:  

Mesh：

Substances：

Year:  1995        PMID： 7695322      PMCID： PMC162525          DOI： 10.1128/AAC.39.1.271

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

Review 1.  Treatment and diagnosis of infections caused by drug-resistant Streptococcus pneumoniae.

Authors:  M R Jacobs
Journal:  Clin Infect Dis       Date:  1992-07       Impact factor: 9.079

Review 2.  Antimicrobial resistance in Streptococcus pneumoniae: an overview.

Authors:  P C Appelbaum
Journal:  Clin Infect Dis       Date:  1992-07       Impact factor: 9.079

3.  Therapy of acute otitis media: myringotomy, antibiotics, or neither? A double-blind study in children.

Authors:  F L van Buchem; J H Dunk; M A van't Hof
Journal:  Lancet       Date:  1981-10-24       Impact factor: 79.321

4.  Comparison of cefuroxime axetil and amoxicillin-clavulanate suspensions in treatment of acute otitis media with effusion in children.

Authors:  S E McLinn; M Moskal; J Goldfarb; F Bodor; G Aronovitz; R Schwartz; P Self; M J Ossi
Journal:  Antimicrob Agents Chemother       Date:  1994-02       Impact factor: 5.191

5.  Screening for cephalosporin-resistant Streptococcus pneumoniae with the Kirby-Bauer disk susceptibility test.

Authors:  I R Friedland; S Shelton; G H McCracken
Journal:  J Clin Microbiol       Date:  1993-06       Impact factor: 5.948

6.  Risk factors and response to antibiotic therapy in adults with bacteremic pneumonia caused by penicillin-resistant pneumococci.

Authors:  R Pallares; F Gudiol; J Liñares; J Ariza; G Rufi; L Murgui; J Dorca; P F Viladrich
Journal:  N Engl J Med       Date:  1987-07-02       Impact factor: 91.245

7.  Streptococcus pneumoniae resistant to penicillin and chloramphenicol.

Authors:  P C Appelbaum; A Bhamjee; J N Scragg; A F Hallett; A J Bowen; R C Cooper
Journal:  Lancet       Date:  1977-11-12       Impact factor: 79.321
  7 in total
  12 in total

Review 1.  Setting and revising antibacterial susceptibility breakpoints.

Authors:  John Turnidge; David L Paterson
Journal:  Clin Microbiol Rev       Date:  2007-07       Impact factor: 26.132

2.  Eradication by ceftriaxone of Streptococcus pneumoniae isolates with increased resistance to penicillin in cases of acute otitis media.

Authors:  P Gehanno; L Nguyen; B Barry; M Derriennic; F Pichon; J M Goehrs; P Berche
Journal:  Antimicrob Agents Chemother       Date:  1999-01       Impact factor: 5.191

3.  In vivo efficacies of amoxicillin and cefuroxime against penicillin-resistant Streptococcus pneumoniae in a gerbil model of acute otitis media.

Authors:  C Cenjor; C Ponte; A Parra; E Nieto; G García-Calvo; M J Giménez; L Aguilar; F Soriano
Journal:  Antimicrob Agents Chemother       Date:  1998-06       Impact factor: 5.191

4.  Can the choice of antibiotics for therapy of acute otitis media be logical?

Authors:  R Dagan
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1998-01       Impact factor: 3.267

5.  Efficacy of single-dose ceftriaxone in experimental otitis media induced by penicillin- and cephalosporin-resistant Streptococcus pneumoniae.

Authors:  B Barry; M Muffat-Joly; J Bauchet; F Faurisson; P Gehanno; J J Pocidalo; C Carbon
Journal:  Antimicrob Agents Chemother       Date:  1996-09       Impact factor: 5.191

6.  In vivo activities of amoxicillin and amoxicillin-clavulanate against Streptococcus pneumoniae: application to breakpoint determinations.

Authors:  D Andes; W A Craig
Journal:  Antimicrob Agents Chemother       Date:  1998-09       Impact factor: 5.191

7.  Mortality from invasive pneumococcal pneumonia in the era of antibiotic resistance, 1995-1997.

Authors:  D R Feikin; A Schuchat; M Kolczak; N L Barrett; L H Harrison; L Lefkowitz; A McGeer; M M Farley; D J Vugia; C Lexau; K R Stefonek; J E Patterson; J H Jorgensen
Journal:  Am J Public Health       Date:  2000-02       Impact factor: 9.308

8.  Prevalence of antimicrobial-resistant pathogens in middle ear fluid: multinational study of 917 children with acute otitis media.

Authors:  M R Jacobs; R Dagan; P C Appelbaum; D J Burch
Journal:  Antimicrob Agents Chemother       Date:  1998-03       Impact factor: 5.191

Review 9.  New concepts in the pathophysiology and management of middle ear disease in childhood.

Authors:  S I Pelton
Journal:  Drugs       Date:  1996       Impact factor: 9.546

10.  Discordant minimum inhibitory concentration analysis: a new path to licensure for anti-infective drugs.

Authors:  Dean Follmann; Erica Brittain; John H Powers
Journal:  Clin Trials       Date:  2013       Impact factor: 2.486
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.