Literature DB >> 7694804

Serum interleukin-1 beta is increased in cluster headache.

P Martelletti1, M Granata, M Giacovazzo.   

Abstract

We measured serum interleukin-1 beta (IL-1 beta) in 24 episodic cluster headache (CH) patients and 45 normal controls using a specific ELISA method. There was an increase in IL-1 beta in all CH patients compared to controls. IL-1 beta was further increased during the ictal phase of CH compared to patients between attacks and normal individuals. Between attacks, IL-1 beta was also significantly increased compared to controls. We suggest that these results represent an activation of the immune system in CH.

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Year:  1993        PMID: 7694804     DOI: 10.1046/j.1468-2982.1993.1305343.x

Source DB:  PubMed          Journal:  Cephalalgia        ISSN: 0333-1024            Impact factor:   6.292


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