Literature DB >> 7694406

The TINS/TiPS Lecture. The molecular biology of mammalian glutamate receptor channels.

P H Seeburg1.   

Abstract

In native brain membranes the principal excitatory neurotransmitter L-glutamate activates cation-conducting channels with distinct biophysical and pharmacological properties. Molecular cloning has revealed the existence of 16 channel subunits that can assemble in homomeric or heteromeric configurations in vitro to form receptor channels with disparate functional properties. This review describes the different channel types obtained by recombinant means and the genetic mechanisms controlling the expression of functionally important channel structures.

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Year:  1993        PMID： 7694406     DOI： 10.1016/0166-2236(93)90093-2

Source DB:  PubMed          Journal:  Trends Neurosci        ISSN： 0166-2236            Impact factor:   13.837


  168 in total

1.  AMPA receptor activates a G-protein that suppresses a cGMP-gated current.

Authors:  F Kawai; P Sterling
Journal:  J Neurosci       Date:  1999-04-15       Impact factor: 6.167

2.  Sticking together.

Authors:  M B Kennedy
Journal:  Proc Natl Acad Sci U S A       Date:  2000-10-10       Impact factor: 11.205

3.  The Lurcher mutation identifies delta 2 as an AMPA/kainate receptor-like channel that is potentiated by Ca(2+).

Authors:  L P Wollmuth; T Kuner; C Jatzke; P H Seeburg; N Heintz; J Zuo
Journal:  J Neurosci       Date:  2000-08-15       Impact factor: 6.167

4.  cAMP-dependent protein kinase mediates activity-regulated synaptic targeting of NMDA receptors.

Authors:  F T Crump; K S Dillman; A M Craig
Journal:  J Neurosci       Date:  2001-07-15       Impact factor: 6.167

Review 5.  Understanding the pathology of schizophrenia: recent advances from the study of the molecular architecture of postmortem CNS tissue.

Authors:  B Dean
Journal:  Postgrad Med J       Date:  2002-03       Impact factor: 2.401

6.  Interaction of the AMPA receptor subunit GluR2/3 with PDZ domains regulates hippocampal long-term depression.

Authors:  C H Kim; H J Chung; H K Lee; R L Huganir
Journal:  Proc Natl Acad Sci U S A       Date:  2001-09-25       Impact factor: 11.205

7.  GABA receptors modulate trigeminovascular nociceptive neurotransmission in the trigeminocervical complex.

Authors:  R J Storer; S Akerman; P J Goadsby
Journal:  Br J Pharmacol       Date:  2001-10       Impact factor: 8.739

8.  Phosphorylation of the AMPA receptor subunit GluR2 differentially regulates its interaction with PDZ domain-containing proteins.

Authors:  H J Chung; J Xia; R H Scannevin; X Zhang; R L Huganir
Journal:  J Neurosci       Date:  2000-10-01       Impact factor: 6.167

9.  Requirement of phospholipase C and protein kinase C in cholecystokinin-mediated facilitation of NMDA channel function and anxiety-like behavior.

Authors:  Zhaoyang Xiao; Manoj K Jaiswal; Pan-Yue Deng; Toshimitsu Matsui; Hee-Sup Shin; James E Porter; Saobo Lei
Journal:  Hippocampus       Date:  2011-11-10       Impact factor: 3.899

10.  Plasticity of glutamate and GABAA receptors in the hippocampus of patients with Alzheimer's disease.

Authors:  David M Armstrong; Roxanne Sheffield; Amanda J Mishizen-Eberz; Troy L Carter; Robert A Rissman; Katsuyoshi Mizukami; Milos D Ikonomovic
Journal:  Cell Mol Neurobiol       Date:  2003-10       Impact factor: 5.046
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