Literature DB >> 7693365

Early bidirectional cavopulmonary shunt in young infants. Postoperative course and early results.

A C Chang1, F L Hanley, G Wernovsky, H M Rosenfeld, D L Wessel, R A Jonas, J E Mayer, J E Lock, A R Castaneda.   

Abstract

BACKGROUND: Despite the recent wide applicability of the bidirectional cavopulmonary shunt, there is limited reported experience in performing these shunts in infants 6 months or younger. METHODS AND
RESULTS: Before October 1992, 17 consecutive infants aged 4.2 to 6.5 months (median, 6.1 months) underwent bidirectional cavopulmonary shunts. The diagnoses were hypoplastic left heart syndrome (n = 7), single right ventricle (n = 5), and single left ventricle (n = 5). All but 2 patients had prior palliative surgery. The bidirectional cavopulmonary shunt was performed early on an elective basis in 9 patients; the remaining patients had progressive cyanosis (6 patients), severe ventricular failure (1 patient), and coexisting restrictive bulboventricular foramen (1 patient). The median preoperative pulmonary arterial pressure and pulmonary vascular resistance were 15 mm Hg and 2.3 U.m2, respectively. One patient died; the overall hospital survival was 94%. The most common postoperative problem was transient systemic hypertension, observed in 14 (88%) of 16 survivors. Systemic arterial oxygen saturation increased from a median of 75% before surgery to a median of 85% after surgery (P < .05). The median hospital stay was 6 days. There were no late deaths during follow-up (median, 12.4 months). At postoperative cardiac catheterization performed in 9 of 16 survivors, there was no evidence of severe hypoxemia, shunt narrowing, or pulmonary arteriovenous fistulas. Of the 16 survivors, 6 have had a subsequent Fontan operation at a median age of 1.9 years; there were 5 survivors.
CONCLUSIONS: Early bidirectional cavopulmonary shunt in young infants has shown encouraging early results and provides improved oxygenation with low morbidity and mortality. We speculate that an early bidirectional cavopulmonary shunt on an elective basis may reduce the deleterious sequelae of chronic hypoxemia, long-term ventricular volume overload, and repeated palliative procedures, thus yielding a more suitable Fontan candidate.

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Year:  1993        PMID: 7693365

Source DB:  PubMed          Journal:  Circulation        ISSN: 0009-7322            Impact factor:   29.690


  8 in total

1.  [The role of bidirectional cavopulmonary shunt on selection of Fontan patients].

Authors:  Y Cho; T Katogi; R Aeba; Y Inoue; K Moro; T Omoto; Y Nakao; S Kawada
Journal:  Jpn J Thorac Cardiovasc Surg       Date:  1998-12

2.  Surgical preconditioning and completion of total cavopulmonary connection by interventional cardiac catheterisation: a new concept.

Authors:  G Hausdorf; M Schneider; W Konertz
Journal:  Heart       Date:  1996-04       Impact factor: 5.994

3.  Risk factors for failed staged palliation after bidirectional Glenn in infants who have undergone stage one palliation.

Authors:  Kevin G Friedman; Joshua W Salvin; David Wypij; Yared Gurmu; Emile A Bacha; David W Brown; Peter C Laussen; Mark A Scheurer
Journal:  Eur J Cardiothorac Surg       Date:  2011-03-05       Impact factor: 4.191

4.  The Optimal Timing of Stage 2 Palliation for Hypoplastic Left Heart Syndrome: An Analysis of the Pediatric Heart Network Single Ventricle Reconstruction Trial Public Data Set.

Authors:  James M Meza; Edward J Hickey; Eugene H Blackstone; Robert D B Jaquiss; Brett R Anderson; William G Williams; Sally Cai; Glen S Van Arsdell; Tara Karamlou; Brian W McCrindle
Journal:  Circulation       Date:  2017-07-07       Impact factor: 29.690

5.  Double inlet left ventricle.

Authors:  Himeshkumar Vyas; Donald J Hagler
Journal:  Curr Treat Options Cardiovasc Med       Date:  2007-10

Review 6.  Comparison of dynamic brain metabolism during antegrade cerebral perfusion versus deep hypothermic circulatory arrest using proton magnetic resonance spectroscopy.

Authors:  Frank L Hanley; Hiroki Ito; Meng Gu; Ralph Hurd; R Kirk Riemer; Daniel Spielman
Journal:  J Thorac Cardiovasc Surg       Date:  2019-11-05       Impact factor: 6.439

Review 7.  Decision-Making for Surgery in the Management of Patients with Univentricular Heart.

Authors:  Ryan Robert Davies; Christian Pizarro
Journal:  Front Pediatr       Date:  2015-07-27       Impact factor: 3.418

Review 8.  Hypoplastic left heart syndrome: from comfort care to long-term survival.

Authors:  Mouhammad Yabrodi; Christopher W Mastropietro
Journal:  Pediatr Res       Date:  2016-10-04       Impact factor: 3.756

  8 in total

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