Literature DB >> 7692078

Haemoglobin F and A2 in Nigerian children with sickle cell anaemia.

O J Fatunde1, A B Scott-Emuakpor.   

Abstract

The concentration of haemoglobins F and A2 in 132 Hb SS children aged 6 months to 16 years and 50 age- and sex-matched controls has been determined. The mean HbF concentration in Hb SS patients and controls were 9.5 per cent (range 1.7-24.5 per cent) and 1.5 per cent (range 0.5-14.4 per cent) respectively while HbA2 concentrations were 2.7 per cent (range 1.6-3.7 per cent) and 2.4 per cent (range 1.3-3.9 per cent) respectively. For 18 Hb SS patients seen in the stable state and during vaso-occlusive crisis, there was no significant difference in HbF concentration between the two states.

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Year:  1993        PMID: 7692078     DOI: 10.1093/tropej/39.4.251

Source DB:  PubMed          Journal:  J Trop Pediatr        ISSN: 0142-6338            Impact factor:   1.165


  2 in total

1.  Evaluation of high performance liquid chromatography (HPLC) pattern and prevalence of beta-thalassaemia trait among sickle cell disease patients in Lagos, Nigeria.

Authors:  Titilope Adeyemo; Oyesola Ojewunmi; Ajoke Oyetunji
Journal:  Pan Afr Med J       Date:  2014-05-22

2.  Foetal haemoglobin and disease severity in sickle cell anaemia patients in Kampala, Uganda.

Authors:  Lena Mpalampa; Christopher M Ndugwa; Henry Ddungu; Richard Idro
Journal:  BMC Blood Disord       Date:  2012-09-07
  2 in total

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