Literature DB >> 7691132

Cell division, chromosomal aberration, and micronuclei formation in human peripheral blood lymphocytes. Effect of stannic chloride on donor's age.

B B Ganguly1.   

Abstract

Age related cytotoxicity of stannic chloride was evaluated in human lymphocytes considering mitotic index (MI), damaged cell (DC), chromosome aberration (CA), and micronuclei formation (MNC) as endpoints. Significant elevation of DCs, CAs, MNCs, and reduction of MI were observed in all classified age groups compared to each control set. The mean frequencies of abnormalities show a statistically significant increase with subject's age. Linearity of the effect of age was common for both untreated and treated lymphocytes of both sexes.

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Year:  1993        PMID: 7691132     DOI: 10.1007/BF02783982

Source DB:  PubMed          Journal:  Biol Trace Elem Res        ISSN: 0163-4984            Impact factor:   3.738


  14 in total

1.  Chromosomal aberration and sister-chromatid exchange frequencies in peripheral blood lymphocytes of a large human population sample. II. Extension of age range.

Authors:  M A Bender; R J Preston; R C Leonard; B E Pyatt; P C Gooch
Journal:  Mutat Res       Date:  1989-06       Impact factor: 2.433

2.  Frequency of chromosome aberrations induced by trimethyltin chloride in human peripheral blood lymphocytes in vitro: related to age of donors.

Authors:  B B Ghosh; G Talukder; A Sharma
Journal:  Mech Ageing Dev       Date:  1991-02       Impact factor: 5.432

3.  Chromosome aberrations in individuals occupationally exposed to ethylene oxide, and in a large control population.

Authors:  S M Galloway; P K Berry; W W Nichols; S R Wolman; K A Soper; P D Stolley; P Archer
Journal:  Mutat Res       Date:  1986 Apr-May       Impact factor: 2.433

4.  Frequency of micronuclei induced in peripheral lymphocytes by trimethyltin chloride.

Authors:  B B Ghosh; G Talukder; A Sharma
Journal:  Mutat Res       Date:  1990-09       Impact factor: 2.433

5.  Occupational and environmental risks in and around a smelter in northern Sweden. IV. Chromosomal aberrations in workers exposed to lead.

Authors:  I Nordenson; G Beckman; L Beckman; S Nordström
Journal:  Hereditas       Date:  1978       Impact factor: 3.271

6.  Cytotoxic effects of trimethyltin chloride on human peripheral blood lymphocytes in vitro.

Authors:  B B Ghosh; G Talukder; A Sharma
Journal:  Hum Toxicol       Date:  1989-09

7.  Screening human populations for chromosome aberrations.

Authors:  A Norman; D Bass; D Roe
Journal:  Mutat Res       Date:  1985-07       Impact factor: 2.433

8.  A cytogenetic study of papaya workers exposed to ethylene dibromide.

Authors:  K Steenland; A Carrano; J Ratcliffe; D Clapp; L Ashworth; T Meinhardt
Journal:  Mutat Res       Date:  1986-06       Impact factor: 2.433

9.  The effect of age on the frequency of sperm chromosomal abnormalities in normal men.

Authors:  R H Martin; A W Rademaker
Journal:  Am J Hum Genet       Date:  1987-09       Impact factor: 11.025

10.  The effect of tin chloride on the structure and function of DNA in human white blood cells.

Authors:  J R McLean; H C Birnboim; R Pontefact; J G Kaplan
Journal:  Chem Biol Interact       Date:  1983-09-01       Impact factor: 5.192

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