Literature DB >> 7691131

Effect of copper sulfate on experimental atherosclerosis.

M Vlad1, E Bordas, R Tomus, D Sava, E Farkas, G Uza.   

Abstract

Serum copper concentration increases significantly (p < 0.01) in rats with experimental atherosclerosis compared to a control group. The serum zinc, the zinc, and copper concentration in abdominal aorta and in liver decreases significantly (p < 0.05) compared to the control group. Administration of copper sulfate for 100 d in these animals induces a significant increase of serum copper (p < 0.01), decrease of serum cholesterol (p < 0.05) and increase of liver copper concentration as compared with the group fed only a high cholesterol diet. In the aorta of these animals the copper concentration increases and edema and lipid infiltration are considerably less than in the group of animals fed only a high lipid diet.

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Year:  1993        PMID： 7691131     DOI： 10.1007/BF02783981

Source DB:  PubMed          Journal:  Biol Trace Elem Res        ISSN： 0163-4984            Impact factor:   3.738


  9 in total

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Authors:  L M Klevay
Journal:  Am J Clin Nutr       Date:  1973-10       Impact factor: 7.045

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Authors:  K G Allen; L M Klevay
Journal:  Atherosclerosis       Date:  1978-11       Impact factor: 5.162

3.  High-density lipoprotein cholesteryl ester and protein catabolism in hypercholesterolemic rats induced by copper deficiency.

Authors:  T P Carr; K Y Lei
Journal:  Metabolism       Date:  1990-05       Impact factor: 8.694

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Authors:  K Y Lei
Journal:  J Nutr       Date:  1983-11       Impact factor: 4.798

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Authors:  L M Klevay; L Inman; L K Johnson; M Lawler; J R Mahalko; D B Milne; H C Lukaski; W Bolonchuk; H H Sandstead
Journal:  Metabolism       Date:  1984-12       Impact factor: 8.694

6.  [Serum zinc and copper in hypercholesterolemia].

Authors:  Y Thuillier-Juteau; M C Jaudon; J P Clavel; J Delattre; A Galli
Journal:  Pathol Biol (Paris)       Date:  1987-04

7.  In vivo apoprotein catabolism of high density lipoproteins in copper-deficient, hypercholesterolemic rats.

Authors:  T P Carr; K Y Lei
Journal:  Proc Soc Exp Biol Med       Date:  1989-09

8.  Apolipoprotein E-rich HDL binding to liver plasma membranes in copper-deficient rats.

Authors:  C A Hassel; T P Carr; J A Marchello; K Y Lei
Journal:  Proc Soc Exp Biol Med       Date:  1988-03

9.  Serum zinc and copper in patients with atherosclerosis and thromboangiitis obliterans.

Authors:  G Uza; R Vlaicu
Journal:  Biol Trace Elem Res       Date:  1989-06       Impact factor: 3.738
  9 in total
  4 in total

1.  Dietary Cholesterol Supplements Disturb Copper Homeostasis in Multiple Organs in Rabbits: Aorta Copper Concentrations Negatively Correlate with the Severity of Atherosclerotic Lesions.

Authors:  Hualin Li; Lijun Zhao; Tao Wang; Y James Kang
Journal:  Biol Trace Elem Res       Date:  2021-03-04       Impact factor: 3.738

2.  The effects of coadministration of dietary copper and zinc supplements on atherosclerosis, antioxidant enzymes and indices of lipid peroxidation in the cholesterol-fed rabbit.

Authors:  Eman M Alissa; Suhad M Bahijri; David J Lamb; Gordon A A Ferns
Journal:  Int J Exp Pathol       Date:  2004-10       Impact factor: 1.925

3.  Effect of cuprofilin on experimental atherosclerosis.

Authors:  M Vlad; E Bordas; E Caseanu; G Uza; E Creteanu; C Polinicenco
Journal:  Biol Trace Elem Res       Date:  1995-04       Impact factor: 3.738

4.  Atherosclerotic lesion-specific copper delivery suppresses atherosclerosis in high-cholesterol-fed rabbits.

Authors:  Na Wang; Xinwen Xu; Hualin Li; Qipu Feng; Hongge Wang; Y James Kang
Journal:  Exp Biol Med (Maywood)       Date:  2021-09-16
  4 in total

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