Literature DB >> 7691129

Alterations in the hepatic enzymes following experimental lead poisoning.

B Nehru1, S Kaushal.   

Abstract

An investigation on the influence of lead toxicity on some of the hepatic enzymes was studied in rats both after a shorter interval of 15 d and after longer intervals of 60 and 90 d. Three different doses of lead as 5, 10, and 50 mg/kg body wt were administered orally on every alternate day. Whereas significant inhibition of succinic dehydrogenase was seen following lead poisoning, the activity acid and alkaline phosphatase increased with lead intoxication. The histoarchitecture of the liver was grossly intact. Liver accumulated less lead compared to kidney at 60 and 90 d.

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Year:  1993        PMID： 7691129     DOI： 10.1007/BF02783979

Source DB:  PubMed          Journal:  Biol Trace Elem Res        ISSN： 0163-4984            Impact factor:   3.738


  11 in total

1.  Effect of automobile exhaust on the distribution of trace elements and its modulation following Fe, Cu, and Zn supplementation.

Authors:  S Kumar; S Singh; D Mehta; R R Garg; M L Garg; N Singh; P C Mangal; P N Trehan
Journal:  Biol Trace Elem Res       Date:  1991-10       Impact factor: 3.738

2.  Colorimetric Estimation of Succinic Dehydrogenase by Triphenyltetrazolium Chloride.

Authors:  E Kun; L G Abood
Journal:  Science       Date:  1949-02-11       Impact factor: 47.728

Review 3.  Biochemical effects of mercury, cadmium, and lead.

Authors:  B L Vallee; D D Ulmer
Journal:  Annu Rev Biochem       Date:  1972       Impact factor: 23.643

4.  Experimental oral lead toxicity in young dogs. Clinical and morphologic effects.

Authors:  H D Stowe; R A Goyer; M Krigman; M Wilson; M Cates
Journal:  Arch Pathol       Date:  1973-02

5.  The behavior of some enzymes in the liver in the course of subacute experimental lead poisoning.

Authors:  Z Zegarska; W Zegarski
Journal:  Acta Med Pol       Date:  1968

6.  Chronic low-level lead toxicity in the rat. III. An integrated assessment of long-term toxicity with special reference to the kidney.

Authors:  B A Fowler; C A Kimmel; J S Woods; E E McConnell; L D Grant
Journal:  Toxicol Appl Pharmacol       Date:  1980-10       Impact factor: 4.219

7.  Identification of lead-binding components in rat liver: in vivo study.

Authors:  E Sabbioni; E Marafante
Journal:  Chem Biol Interact       Date:  1976-09       Impact factor: 5.192

8.  Lead and liver cell proliferation. Effect of repeated administrations.

Authors:  G M Ledda-Columbano; A Columbano; P Pani
Journal:  Am J Pathol       Date:  1983-12       Impact factor: 4.307

Review 9.  Current issues in the epidemiology and toxicology of occupational exposure to lead.

Authors:  P J Landrigan
Journal:  Environ Health Perspect       Date:  1990-11       Impact factor: 9.031

10.  Ultrastructural transformation in mitochondria isolated from kidneys of normal and lead-intoxicated rats.

Authors:  R A Goyer; R Krall
Journal:  J Cell Biol       Date:  1969-05       Impact factor: 10.539
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  4 in total

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Authors:  Nahed Amri; Fatma Rahmouni; Med Ali Chokri; Tarek Rebai; Riadh Badraoui
Journal:  Environ Sci Pollut Res Int       Date:  2017-06-13       Impact factor: 4.223

2.  Histological and histochemical alterations in the liver induced by lead chronic toxicity.

Authors:  Bashir M Jarrar; Noory T Taib
Journal:  Saudi J Biol Sci       Date:  2012-01-05       Impact factor: 4.219

3.  Parental Lead Exposure Promotes Neurobehavioral Disorders and Hepatic Dysfunction in Mouse Offspring.

Authors:  Hasan Ul Banna; Adiba Anjum; Sheta Biswas; Victor Mondal; Abu Eabrahim Siddique; Apurba Kumar Roy; Farjana Nikkon; Azizul Haque; Seiichiro Himeno; Kazi Abdus Salam; Khaled Hossain; Zahangir Alam Saud
Journal:  Biol Trace Elem Res       Date:  2021-04-08       Impact factor: 3.738

4.  Lead Affects Vitamin D Metabolism in Rats.

Authors:  Abdur Rahman; Ameena A Al-Awadi; Khalid M Khan
Journal:  Nutrients       Date:  2018-02-26       Impact factor: 5.717
  4 in total

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