Literature DB >> 7691001

From white spots to stem cells: the role of the Kit receptor in mammalian development.

R A Fleischman1.   

Abstract

The Kit tyrosine kinase membrane receptor is essential for melanogenesis, gametogenesis and hematopoiesis during embryonic development and postnatal life. This review summarizes the genetic evidence implicating Kit and its ligand, Steel factor, in the control of stem cell proliferation, migration and survival, with emphasis on mutations in the human and mouse genes.

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Year:  1993        PMID： 7691001     DOI： 10.1016/0168-9525(93)90015-a

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  25 in total

Review 1.  Targeting KIT in melanoma: a paradigm of molecular medicine and targeted therapeutics.

Authors:  Scott E Woodman; Michael A Davies
Journal:  Biochem Pharmacol       Date:  2010-05-08       Impact factor: 5.858

Review 2.  Gastrointestinal stromal tumors (GISTs): an updated experience.

Authors:  Anastasios Machairas; Eva Karamitopoulou; Dimitrios Tsapralis; Theodore Karatzas; Nickolas Machairas; Evangelos P Misiakos
Journal:  Dig Dis Sci       Date:  2010-08-20       Impact factor: 3.199

3.  KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors.

Authors:  M L Lux; B P Rubin; T L Biase; C J Chen; T Maclure; G Demetri; S Xiao; S Singer; C D Fletcher; J A Fletcher
Journal:  Am J Pathol       Date:  2000-03       Impact factor: 4.307

4.  Cerebellar disorganization characteristic of reeler in scrambler mutant mice despite presence of reelin.

Authors:  D Goldowitz; R C Cushing; E Laywell; G D'Arcangelo; M Sheldon; H O Sweet; M Davisson; D Steindler; T Curran
Journal:  J Neurosci       Date:  1997-11-15       Impact factor: 6.167

5.  Heterozygous kit mutants with little or no apparent anemia exhibit large defects in overall hematopoietic stem cell function.

Authors:  Yashoda Sharma; Clinton M Astle; David E Harrison
Journal:  Exp Hematol       Date:  2007-02       Impact factor: 3.084

6.  Identification of X-linked genes required for migration and programmed cell death of Drosophila melanogaster germ cells.

Authors:  Clark R Coffman; Rachel C Strohm; Fredrick D Oakley; Yukiko Yamada; Danielle Przychodzin; Robert E Boswell
Journal:  Genetics       Date:  2002-09       Impact factor: 4.562

7.  Structural basis for KIT receptor tyrosine kinase inhibition by antibodies targeting the D4 membrane-proximal region.

Authors:  Andrey V Reshetnyak; Bryce Nelson; Xiarong Shi; Titus J Boggon; Alevtina Pavlenco; Elizabeth M Mandel-Bausch; Francisco Tome; Yoshihisa Suzuki; Sachdev S Sidhu; Irit Lax; Joseph Schlessinger
Journal:  Proc Natl Acad Sci U S A       Date:  2013-10-14       Impact factor: 11.205

Review 8.  Cardiomyogenic stem and progenitor cell plasticity and the dissection of cardiopoiesis.

Authors:  Maria Grazia Perino; Satoshi Yamanaka; Jinliang Li; Anna M Wobus; Kenneth R Boheler
Journal:  J Mol Cell Cardiol       Date:  2008-05-11       Impact factor: 5.000

9.  Stem cell factor-mediated wild-type KIT receptor activation is critical for gastrointestinal stromal tumor cell growth.

Authors:  Chen-Guang Bai; Xiao-Wei Hou; Feng Wang; Cen Qiu; Yan Zhu; Ling Huang; Jing Zhao; Jing-Jing Xu; Da-Lie Ma
Journal:  World J Gastroenterol       Date:  2012-06-21       Impact factor: 5.742

10.  The c-kit signaling pathway is involved in the development of persistent pain.

Authors:  Yan-Gang Sun; Neilia G Gracias; Julie Kosto Drobish; Michael R Vasko; Robert W Gereau; Zhou-Feng Chen
Journal:  Pain       Date:  2009-05-13       Impact factor: 6.961
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