Literature DB >> 7689553

A novel human cDNA with a predicted protein similar to lysyl oxidase maps to chromosome 15q24-q25.

K Kenyon1, W S Modi, S Contente, R M Friedman.   

Abstract

A novel human cDNA with a predicted protein homologous to the carboxyl end of lysyl oxidase, an extracellular enzyme involved in the maturation of collagen and elastin, has been isolated. The homology to lysyl oxidase begins exactly at the position of the exon 1/exon 2 boundary in the mouse gene (Contente, S., Csiszar, K., Kenyon, K., and Friedman, R. M. (1993) Genomics 16, 395-400). This lysyl oxidase-like gene, which appears to be no larger than 22.1 kilobases, codes for a single polyadenylated RNA species of 2.48 kilobases and has been mapped to chromosome 15q24-q25.

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Year:  1993        PMID： 7689553

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  17 in total

Review 1.  Characterizing a human lysyl oxidase chromosomal domain.

Authors:  R P Martins; S A Krawetz
Journal:  Mol Biotechnol       Date:  2000-07       Impact factor: 2.695

2.  Genetic mapping of lysyl oxidase-2 (Loxl) on mouse chromosome 9.

Authors:  V T Tchernev; T P Yang; S F Kingsmore
Journal:  Mamm Genome       Date:  1997-08       Impact factor: 2.957

Review 3.  Diverse biological functions of extracellular collagen processing enzymes.

Authors:  Philip C Trackman
Journal:  J Cell Biochem       Date:  2005-12-01       Impact factor: 4.429

4.  Lysyl oxidase gene expression in the stromal reaction to in situ and invasive ductal breast carcinoma.

Authors:  S Peyrol; M Raccurt; F Gerard; C Gleyzal; J A Grimaud; P Sommer
Journal:  Am J Pathol       Date:  1997-02       Impact factor: 4.307

5.  Localization and activity of lysyl oxidase within nuclei of fibrogenic cells.

Authors:  W Li; K Nellaiappan; T Strassmaier; L Graham; K M Thomas; H M Kagan
Journal:  Proc Natl Acad Sci U S A       Date:  1997-11-25       Impact factor: 11.205

6.  Lysyl oxidase is essential for normal development and function of the respiratory system and for the integrity of elastic and collagen fibers in various tissues.

Authors:  Joni M Mäki; Raija Sormunen; Sari Lippo; Riitta Kaarteenaho-Wiik; Raija Soininen; Johanna Myllyharju
Journal:  Am J Pathol       Date:  2005-10       Impact factor: 4.307

7.  The association of LOXL1 polymorphisms with exfoliation syndrome/glaucoma: Meta-analysis.

Authors:  Qing-Shan Ji; Bing Qi; Yue-Chun Wen; Lian Liu; Xiao-Ling Guo; Guo-Cheng Yu; Jing-Xiang Zhong
Journal:  Int J Ophthalmol       Date:  2015-02-18       Impact factor: 1.779

8.  Systematic screening of lysyl oxidase-like (LOXL) family genes demonstrates that LOXL2 is a susceptibility gene to intracranial aneurysms.

Authors:  Hiroyuki Akagawa; Akira Narita; Haruhiko Yamada; Atsushi Tajima; Boris Krischek; Hidetoshi Kasuya; Tomokatsu Hori; Motoo Kubota; Naokatsu Saeki; Akira Hata; Tohru Mizutani; Ituro Inoue
Journal:  Hum Genet       Date:  2007-02-08       Impact factor: 4.132

9.  Lysyl oxidase (lox) gene deficiency affects osteoblastic phenotype.

Authors:  N Pischon; J M Mäki; P Weisshaupt; N Heng; A H Palamakumbura; P N'Guessan; A Ding; R Radlanski; H Renz; T A L J J Bronckers; J Myllyharju; A M Kielbassa; B M Kleber; J-P Bernimoulin; P C Trackman
Journal:  Calcif Tissue Int       Date:  2009-05-21       Impact factor: 4.333

10.  Genotype-correlated expression of lysyl oxidase-like 1 in ocular tissues of patients with pseudoexfoliation syndrome/glaucoma and normal patients.

Authors:  Ursula Schlötzer-Schrehardt; Francesca Pasutto; Pascal Sommer; Ian Hornstra; Friedrich E Kruse; Gottfried O H Naumann; André Reis; Matthias Zenkel
Journal:  Am J Pathol       Date:  2008-10-30       Impact factor: 4.307
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