| Literature DB >> 7689092 |
N F Hallam1, M L Fletcher, S J Read, A M Majid, J B Kurtz, C R Rizza.
Abstract
Sexual transmission of hepatitis C virus (HCV) was studied between 104 anti-HCV positive index cases (99 haemophilic men, five women) who have attended the Oxford Haemophilia Centre and 104 (98 female, 6 male) longstanding sexual partners. Ninety-one percent of the index cases were HCV RNA positive by the polymerase chain reaction (PCR) and 56% were anti-human immunodeficiency virus (HIV) positive. Three (2.9%) sexual partners (each a female partner of a different HCV RNA positive haemophilic man) were anti-HCV, and HCV RNA, positive. All had other risk factors for HCV infection. Of 59 partners who were tested for anti-HIV four (7%) were positive and only one of these was also anti-HCV positive. There was no association between HIV positivity in the index cases and HCV positivity in their partners. Our results confirm a low risk of sexual transmission of HCV.Entities:
Mesh：
Substances：
Year: 1993 PMID： 7689092 DOI： 10.1002/jmv.1890400315
Source DB: PubMed Journal: J Med Virol ISSN： 0146-6615 Impact factor: 2.327