Literature DB >> 7688541

Determination of superoxide dismutase-like activity in some divalent metal saccharinates.

M C Apella1, R Totaro, E J Baran.   

Abstract

The superoxide-dismutase-like activity of a series of divalent metal saccharinates of general stoichiometry [MII(Sac)2(H2O)4].2H2O (with MII = Mn,Fe,Co,Ni,Cu,Zn) has been investigated using the nitroblue tetrazolium O2- reduction assay. The results show that all these complexes possess the capability to dismutate the superoxide anion generated in the xanthine/xanthine oxidase system. Interestingly, the greatest activity is shown by the corresponding copper complex. The results are discussed and compared with those obtained for native superoxide dismutase, which was tested under the same experimental conditions.

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Year:  1993        PMID: 7688541     DOI: 10.1007/BF02783803

Source DB:  PubMed          Journal:  Biol Trace Elem Res        ISSN: 0163-4984            Impact factor:   3.738


  8 in total

1.  Novel iron complexes behave like superoxide dismutase in vivo.

Authors:  T Nagano; T Hirano; M Hirobe
Journal:  Free Radic Res Commun       Date:  1991

2.  Reactivity of antiinflammatory and superoxide dismutase active Cu(II)-salicylates.

Authors:  U Weser; C Richter; A Wendel; M Younes
Journal:  Bioinorg Chem       Date:  1978

3.  An iron-containing superoxide dismutase from Escherichia coli.

Authors:  F J Yost; I Fridovich
Journal:  J Biol Chem       Date:  1973-07-25       Impact factor: 5.157

4.  Superoxide dismutase from escherichia coli B. A new manganese-containing enzyme.

Authors:  B B Keele; J M McCord; I Fridovich
Journal:  J Biol Chem       Date:  1970-11-25       Impact factor: 5.157

5.  Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein).

Authors:  J M McCord; I Fridovich
Journal:  J Biol Chem       Date:  1969-11-25       Impact factor: 5.157

6.  The presence of zinc in human cytocuprein and some properties of the apoprotein.

Authors:  R J Carrico; H F Deutsch
Journal:  J Biol Chem       Date:  1970-02-25       Impact factor: 5.157

7.  Superoxide dismutase: improved assays and an assay applicable to acrylamide gels.

Authors:  C Beauchamp; I Fridovich
Journal:  Anal Biochem       Date:  1971-11       Impact factor: 3.365

8.  Superoxide dismutase mimics based on iron in vivo.

Authors:  T Nagano; T Hirano; M Hirobe
Journal:  J Biol Chem       Date:  1989-06-05       Impact factor: 5.157

  8 in total
  1 in total

1.  In Vitro Assessment of Antimicrobial, Antioxidant, and Cytotoxic Properties of Saccharin-Tetrazolyl and -Thiadiazolyl Derivatives: The Simple Dependence of the pH Value on Antimicrobial Activity.

Authors:  Luís M T Frija; Epole Ntungwe; Przemysław Sitarek; Joana M Andrade; Monika Toma; Tomasz Śliwiński; Lília Cabral; M Lurdes S Cristiano; Patrícia Rijo; Armando J L Pombeiro
Journal:  Pharmaceuticals (Basel)       Date:  2019-11-12
  1 in total

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