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Literature DB >> 76883

Genetically determined defcts of oxidation at carbon centres of drugs.

R L Smith, J R Idle, A A Mahgoub, T P Sloan, R Lancaster.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 1978 PMID： 76883 DOI： 10.1016/s0140-6736(78)90724-9

Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321

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2 in total

Review 1. Genetically determined variability in acetylation and oxidation. Therapeutic implications.

Authors: D W Clark
Journal: Drugs Date: 1985-04 Impact factor: 9.546

2. Functional Significance of Cytochrome P450 1A2 Allelic Variants, P450 1A28, 15, and *16 (R456H, P42R, and R377Q).

Authors: Young-Ran Lim; In-Hyeok Kim; Songhee Han; Hyoung-Goo Park; Mi-Jung Ko; Young-Jin Chun; Chul-Ho Yun; Donghak Kim
Journal: Biomol Ther (Seoul) Date: 2015-03-01 Impact factor: 4.634

2 in total

Genetically determined defcts of oxidation at carbon centres of drugs.

Review 1. Genetically determined variability in acetylation and oxidation. Therapeutic implications.

2. Functional Significance of Cytochrome P450 1A2 Allelic Variants, P450 1A2*8, *15, and *16 (R456H, P42R, and R377Q).

2. Functional Significance of Cytochrome P450 1A2 Allelic Variants, P450 1A28, 15, and *16 (R456H, P42R, and R377Q).