Successful treatment of cornual pregnancy with 1-day high-dose methotrexate regimen and folinic acid rescue.

This report describes a woman with a cornual pregnancy, documented by laparoscopy and ultrasonography, who was successfully treated with a 1-day high-dose methotrexate regimen and folinic acid rescue. The serum beta-hCG level was 2,260 and increased to 3,060 IU/l on the 5th day after treatment before it fell precipitously to below 250 IU/l 15 days after methotrexate treatment. No side effects were experienced by the patient.