Literature DB >> 7685938

The role of positron emission tomography in the assessment of human neurotransplantation.

G V Sawle1, R Myers.   

Abstract

Positron emission tomography (PET) using tracers of the dopaminergic system has been used to measure striatal function in a small number of parkinsonian patients undergoing neurotransplantation procedures. Some postoperative scans have shown an unequivocal increase in presynaptic dopaminergic function at the graft site, providing evidence of graft survival independent of clinical assessment. Combined PET and magnetic resonance imaging (MRI) images provide the facility to explore the relationship between graft placement, survival and clinical efficacy.

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Year:  1993        PMID: 7685938     DOI: 10.1016/0166-2236(93)90143-a

Source DB:  PubMed          Journal:  Trends Neurosci        ISSN: 0166-2236            Impact factor:   13.837


  6 in total

Review 1.  Aspects of PET imaging relevant to the assessment of striatal transplantation in Huntington's disease.

Authors:  L Besret; A L Kendall; S B Dunnett
Journal:  J Anat       Date:  2000-05       Impact factor: 2.610

Review 2.  Behavioural consequences of neural transplantation.

Authors:  S B Dunnett
Journal:  J Neurol       Date:  1994-12       Impact factor: 4.849

3.  Short-term GDNF treatment provides long-term rescue of lesioned nigral dopaminergic neurons in a rat model of Parkinson's disease.

Authors:  C Winkler; H Sauer; C S Lee; A Björklund
Journal:  J Neurosci       Date:  1996-11-15       Impact factor: 6.167

Review 4.  Imaging the head: functional imaging.

Authors:  G V Sawle
Journal:  J Neurol Neurosurg Psychiatry       Date:  1995-02       Impact factor: 10.154

5.  Studies on the striatal dopamine uptake system of weaver mutant mice and effects of ventral mesencephalic grafts.

Authors:  L C Triarhou; E H Stotz; W C Low; J Norton; B Ghetti; B Landwehrmeyer; J M Palacios; J R Simon
Journal:  Neurochem Res       Date:  1994-11       Impact factor: 3.996

6.  Cistanche tubulosa Protects Dopaminergic Neurons through Regulation of Apoptosis and Glial Cell-Derived Neurotrophic Factor: in vivo and in vitro.

Authors:  Qian Xu; Wen Fan; Shui-Fen Ye; Yi-Bo Cong; Wei Qin; Shi-Ya Chen; Jing Cai
Journal:  Front Aging Neurosci       Date:  2016-12-16       Impact factor: 5.750

  6 in total

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