| Literature DB >> 7685314 |
A Suhrbier1, C Schmidt, A Fernan.
Abstract
Alignment of previously identified HLA B8-restricted cytotoxic T-cell (CTL) epitopes revealed a common motif: x, x, K/R, x, R/K, x, W/Y, x, I/L. Of five motif-conforming peptides tested, ELRSRYWAI was found to represent a new epitope from influenza nucleoprotein (NP). High concentrations of some peptides gave cross-reactive stimulation illustrating the requirement to confirm epitope assignment with recombinant vaccinias and highlighting a potential problem of peptide-based CTL vaccines.Entities:
Mesh:
Substances:
Year: 1993 PMID: 7685314 PMCID: PMC1422045
Source DB: PubMed Journal: Immunology ISSN: 0019-2805 Impact factor: 7.397