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Literature DB >> 7685193

Treatment of drug-induced agranulocytosis with recombinant granulocyte colony-stimulating factor (rh G-CSF).

A Willfort¹, C Lorber, S Kapiotis, S Sertl, R Hainz, P Kirchweger, U Jäger, P A Kyrle, K Lechner, K Geissler.

Abstract

Five patients with drug-induced agranulocytosis received 300 micrograms recombinant human granulocyte colony-stimulating factor (rh G-CSF) subcutaneously twice daily for 2-5 days. G-CSF therapy resulted in a steep increase of the neutrophil count, which was faster than that in patients with spontaneous recovery reported in the literature. In all four patients with infectious complications fever rapidly declined with the increase of granulocytes. G-CSF may be useful in the management of drug-induced agranulocytosis.

Entities: Disease Gene Species

Mesh：

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Year: 1993 PMID： 7685193 DOI： 10.1007/bf01738472

Source DB: PubMed Journal: Ann Hematol ISSN： 0939-5555 Impact factor: 3.673

15 in total

3. Lineage-unrestricted hematologic response to granulocyte colony-stimulating factor in a patient with refractory anemia with excess blasts.

Authors: N Yokose; K Ogata; E An; H Tamura; K Kamikubo; K Dan; T Nomura
Journal: Ann Hematol Date: 1995-03 Impact factor: 3.673

Treatment of drug-induced agranulocytosis with recombinant granulocyte colony-stimulating factor (rh G-CSF).

1. Accelerated recovery from drug-induced agranulocytosis following G-CSF therapy.

Review 2. Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor (1).

3. Successful treatment of chronic idiopathic neutropenia using recombinant granulocyte colony-stimulating factor.

4. Use of granulocyte-macrophage colony stimulating factor for treatment of drug-induced agranulocytosis.

5. Treatment of drug-induced agranulocytosis with granulocyte-colony stimulating factor.

6. Drug-induced agranulocytosis: evidence for the commitment of bone marrow haematopoiesis.

7. Hematologic effects of recombinant human granulocyte colony-stimulating factor in patients with malignancy.

8. Drug-induced agranulocytosis: prognostic factors in a series of 168 episodes.

9. Granulocyte-macrophage colony stimulating factor for the treatment of drug induced agranulocytosis.

10. [Drugs and acute agranulocytosis: analysis of previous drug intake in 42 patients (author's transl)].

1. Erysipelas in neutropenia of unknown origin, successfully treated with r-metHuG-CSF (filgrastim)

2. Risks of rhG-CSF treatment in drug-induced agranulocytosis.

3. Lineage-unrestricted hematologic response to granulocyte colony-stimulating factor in a patient with refractory anemia with excess blasts.

4. Agranulocytosis induced by antithyroid therapy: effects of treatment with granulocyte colony stimulating factor.

5. Methimazole-Induced Aplastic Anemia with Concomitant Hepatitis in a Young Filipina with Graves' Disease.

6. Use of granulocyte colony-stimulating factor in the treatment of methimazole-induced agranulocytosis: a case report.