Literature DB >> 7685014

Polymerase chain reaction cloning of a developmentally regulated member of the sialyltransferase gene family.

B D Livingston1, J C Paulson.   

Abstract

We have cloned a new member of the sialyltransferase gene family from newborn rat brain cDNA using the polymerase chain reaction and degenerate primers based on sequences found in a continuous region of homology present in three previously cloned sialyltransferases. The predicted amino acid sequence of the new gene contains 24 of the 31 amino acids that are invariantly conserved in the previously cloned sialyltransferases and encodes a type II transmembrane protein characteristic of glycosyltransferases. In contrast to previously cloned sialyltransferase genes, the expression of the new gene is highly restricted, being abundantly expressed in newborn brain but not in adult brain or any other adult or newborn tissues.

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Year:  1993        PMID： 7685014

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  26 in total

Review 1.  Sialyltransferases in cancer.

Authors:  F Dall'Olio; M Chiricolo
Journal:  Glycoconj J       Date:  2001 Nov-Dec       Impact factor: 2.916

2.  Sensory experience differentially modulates the mRNA expression of the polysialyltransferases ST8SiaII and ST8SiaIV in postnatal mouse visual cortex.

Authors:  Marie-Claude Bélanger; Graziella Di Cristo
Journal:  PLoS One       Date:  2011-09-21       Impact factor: 3.240

3.  Reversible sialylation: synthesis of cytidine 5'-monophospho-N-acetylneuraminic acid from cytidine 5'-monophosphate with alpha2,3-sialyl O-glycan-, glycolipid-, and macromolecule-based donors yields diverse sialylated products.

Authors:  E V Chandrasekaran; Jun Xue; Jie Xia; Robert D Locke; Khushi L Matta; Sriram Neelamegham
Journal:  Biochemistry       Date:  2007-12-08       Impact factor: 3.162

4.  Localization of beta-galactoside alpha2,6-sialyltransferase gene on pig chromosome 13q4.1.

Authors:  L Saint Oyant-Hibrand; C Rogel-Gaillard; C Renard; R Julien; M Yerle
Journal:  Mamm Genome       Date:  1997-04       Impact factor: 2.957

5.  A beta-1,3-N-acetylglucosaminyltransferase with poly-N-acetyllactosamine synthase activity is structurally related to beta-1,3-galactosyltransferases.

Authors:  D Zhou; A Dinter; R Gutiérrez Gallego; J P Kamerling; J F Vliegenthart; E G Berger; T Hennet
Journal:  Proc Natl Acad Sci U S A       Date:  1999-01-19       Impact factor: 11.205

Review 6.  Biosynthesis and functions of gangliosides: recent advances.

Authors:  K O Lloyd; K Furukawa
Journal:  Glycoconj J       Date:  1998-07       Impact factor: 2.916

7.  Removal of 106 amino acids from the N-terminus of UDP-GlcNAc: alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I does not inactivate the enzyme.

Authors:  M Sarkar; S Pagny; U Unligil; D Joziasse; J Mucha; J Glössl; H Schachter
Journal:  Glycoconj J       Date:  1998-02       Impact factor: 2.916

8.  Multiplex RT-PCR method for the analysis of the expression of human sialyltransferases: application to breast cancer cells.

Authors:  M A Recchi; A Harduin-Lepers; Y Boilly-Marer; A Verbert; P Delannoy
Journal:  Glycoconj J       Date:  1998-01       Impact factor: 2.916

9.  Expression of sialyltransferase is not required for interaction of Neisseria gonorrhoeae with human epithelial cells and human neutrophils.

Authors:  D J McGee; G C Chen; R F Rest
Journal:  Infect Immun       Date:  1996-10       Impact factor: 3.441

10.  Identification of the gonococcal glmU gene encoding the enzyme N-acetylglucosamine 1-phosphate uridyltransferase involved in the synthesis of UDP-GlcNAc.

Authors:  J Ullrich; J P van Putten
Journal:  J Bacteriol       Date:  1995-12       Impact factor: 3.490
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