Literature DB >> 7684252

Monoclonal antibodies directed against T cell epitopes presented by class I MHC antigens.

H T Duc1, P Rucay, S Righenzi, O Halle-Pannenko, P Kourilsky.   

Abstract

Monoclonal antibodies which recognize a synthetic peptide derived from influenza virus nucleoprotein in association with a murine class I MHC molecule (Kd) have been isolated. One such antibody has been characterized and shown to react neither with the peptide nor with the Kd molecule, but only with the Kd-peptide complex. Evidence is given that it recognizes the naturally processed peptide located in the peptide binding groove, i.e. the antigenic moiety presented to T cells.

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Year:  1993        PMID： 7684252     DOI： 10.1093/intimm/5.4.427

Source DB:  PubMed          Journal:  Int Immunol        ISSN： 0953-8178            Impact factor:   4.823


  9 in total

1.  Epitopes of the class I major histocompatibility complex (MHC-I) recognized in the syngeneic or allogeneic context predominantly linked to antigenic peptide loading to its binding groove.

Authors:  P Nguyen van Binh; H T Duc
Journal:  Clin Exp Immunol       Date:  2006-08       Impact factor: 4.330

2.  A recombinant antibody with the antigen-specific, major histocompatibility complex-restricted specificity of T cells.

Authors:  P S Andersen; A Stryhn; B E Hansen; L Fugger; J Engberg; S Buus
Journal:  Proc Natl Acad Sci U S A       Date:  1996-03-05       Impact factor: 11.205

3.  Production, specificity, and functionality of monoclonal antibodies to specific peptide-major histocompatibility complex class II complexes formed by processing of exogenous protein.

Authors:  G Zhong; C Reis e Sousa; R N Germain
Journal:  Proc Natl Acad Sci U S A       Date:  1997-12-09       Impact factor: 11.205

4.  PmpG303-311, a protective vaccine epitope that elicits persistent cellular immune responses in Chlamydia muridarum-immune mice.

Authors:  Raymond M Johnson; Hong Yu; Micah S Kerr; James E Slaven; Karuna P Karunakaran; Robert C Brunham
Journal:  Infect Immun       Date:  2012-03-19       Impact factor: 3.441

5.  Stabilizing mutations increase secretion of functional soluble TCR-Ig fusion proteins.

Authors:  Elin Lunde; Geir Åge Løset; Bjarne Bogen; Inger Sandlie
Journal:  BMC Biotechnol       Date:  2010-08-24       Impact factor: 2.563

6.  Visualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2-MBP 85-99 complex.

Authors:  M Krogsgaard; K W Wucherpfennig; B Cannella; B E Hansen; A Svejgaard; J Pyrdol; H Ditzel; C Raine; J Engberg; L Fugger; B Canella
Journal:  J Exp Med       Date:  2000-04-17       Impact factor: 14.307

7.  Analysis of the expression of peptide-major histocompatibility complexes using high affinity soluble divalent T cell receptors.

Authors:  S M O'Herrin; M S Lebowitz; J G Bieler; B K al-Ramadi; U Utz; A L Bothwell; J P Schneck
Journal:  J Exp Med       Date:  1997-10-20       Impact factor: 14.307

Review 8.  Opportunities and Challenges for Antibodies against Intracellular Antigens.

Authors:  Xiaofeng Yang; Shenxia Xie; Xiaomei Yang; Juan C Cueva; Xiaoqiong Hou; Zhuoran Tang; Hua Yao; Fengzhen Mo; Shihua Yin; Aiqun Liu; Xiaoling Lu
Journal:  Theranostics       Date:  2019-10-15       Impact factor: 11.556

9.  T cell receptor-like recognition of tumor in vivo by synthetic antibody fragment.

Authors:  Keith R Miller; Akiko Koide; Brenda Leung; Jonathan Fitzsimmons; Bryan Yoder; Hong Yuan; Michael Jay; Sachdev S Sidhu; Shohei Koide; Edward J Collins
Journal:  PLoS One       Date:  2012-08-20       Impact factor: 3.240
  9 in total

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