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Literature DB >> 7682272

The "trap" hypothesis of venous ulceration.

Abstract

The pathogenesis of venous ulceration is unknown. We propose that macromolecules leaking into the dermis as a result of venous hypertension bind to or "trap" growth factors and matrix material, which then become unavailable for tissue repair and for the maintenance of tissue integrity.

Entities: Disease

Mesh：

Substances：

Year: 1993 PMID： 7682272 DOI： 10.1016/0140-6736(93)91085-z

Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321

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Cited

28 in total

1. [Possible interventions in impaired wound healing].

Authors: S Coerper; S Beckert; H D Becker
Journal: Chirurg Date: 2004-05 Impact factor: 0.955

2. Tissue Oxygenation Changes to Assess Healing in Venous Leg Ulcers Using Near-Infrared Optical Imaging.

Authors: Rebecca Kwasinski; Cristianne Fernandez; Kevin Leiva; Richard Schutzman; Edwin Robledo; Penelope Kallis; Luis J Borda; Robert Kirsner; Francisco Perez-Clavijo; Anuradha Godavarty
Journal: Adv Wound Care (New Rochelle) Date: 2019-10-16 Impact factor: 4.730

Review 3. National Athletic Trainers' Association Position Statement: Management of Acute Skin Trauma.

Authors: Joel W Beam; Bernadette Buckley; William R Holcomb; Mario Ciocca
Journal: J Athl Train Date: 2017-01-16 Impact factor: 2.860

4. Intralesional administration of epidermal growth factor-based formulation (Heberprot-P) in chronic diabetic foot ulcer: treatment up to complete wound closure.

Authors: José I Fernández-Montequín; Blas Y Betancourt; Gisselle Leyva-Gonzalez; Ernesto L Mola; Katia Galán-Naranjo; Mayte Ramírez-Navas; Sergio Bermúdez-Rojas; Felix Rosales; Elizeth García-Iglesias; Jorge Berlanga-Acosta; Ricardo Silva-Rodriguez; Marianela Garcia-Siverio; Luis H Martinez
Journal: Int Wound J Date: 2009-02 Impact factor: 3.315

5. Intra-lesional injections of recombinant human epidermal growth factor promote granulation and healing in advanced diabetic foot ulcers: multicenter, randomised, placebo-controlled, double-blind study.

Authors: José I Fernández-Montequín; Carmen M Valenzuela-Silva; Odalys González Díaz; William Savigne; Natasha Sancho-Soutelo; Fidel Rivero-Fernández; Pablo Sánchez-Penton; Lourdes Morejón-Vega; Heriberto Artaza-Sanz; Arístides García-Herrera; Cecilio González-Benavides; Carlos M Hernández-Cañete; Alberto Vázquez-Proenza; Jorge Berlanga-Acosta; Pedro A López-Saura
Journal: Int Wound J Date: 2009-12 Impact factor: 3.315

6. Intralesional injections of Citoprot-P (recombinant human epidermal growth factor) in advanced diabetic foot ulcers with risk of amputation.

Authors: José I Fernández-Montequín; Ena Infante-Cristiá; Carmen Valenzuela-Silva; Neobalis Franco-Pérez; William Savigne-Gutierrez; Heriberto Artaza-Sanz; Lourdes Morejón-Vega; Cecilio González-Benavides; Osvaldo Eliseo-Musenden; Elizeth García-Iglesias; Jorge Berlanga-Acosta; Ricardo Silva-Rodríguez; Blas Y Betancourt; Pedro A López-Saura
Journal: Int Wound J Date: 2007-10-22 Impact factor: 3.315

The "trap" hypothesis of venous ulceration.

1. [Possible interventions in impaired wound healing].

2. Tissue Oxygenation Changes to Assess Healing in Venous Leg Ulcers Using Near-Infrared Optical Imaging.

Review 3. National Athletic Trainers' Association Position Statement: Management of Acute Skin Trauma.

4. Intralesional administration of epidermal growth factor-based formulation (Heberprot-P) in chronic diabetic foot ulcer: treatment up to complete wound closure.

5. Intra-lesional injections of recombinant human epidermal growth factor promote granulation and healing in advanced diabetic foot ulcers: multicenter, randomised, placebo-controlled, double-blind study.

6. Intralesional injections of Citoprot-P (recombinant human epidermal growth factor) in advanced diabetic foot ulcers with risk of amputation.

7. Controlled delivery of heparin-binding EGF-like growth factor yields fast and comprehensive wound healing.

8. [Ulcus cruris venosum: surgical debridement, antibiotic therapy and stimulation with thrombocytic growth factors].

Review 9. Optimal treatment of venous (stasis) ulcers in elderly patients.

10. A role for human skin-resident T cells in wound healing.