Literature DB >> 7681997

Results of a randomized clinical trial comparing two radiation schedules in the palliative treatment of brain metastases.

C Haie-Meder1, B Pellae-Cosset, A Laplanche, J L Lagrange, C Tuchais, C Nogues, R Arriagada.   

Abstract

In 216 patients with brain metastases two schedules of brain irradiation were compared in a randomized trial: one course of 18 Gy/3 fractions/3 days versus the same fractionation followed by a second course of radiotherapy with a one-month time interval. The second course was identical to the first one or delivered 25 Gy/10 fractions/14 days. No difference in overall survival, nor in the neurologic response or in the incidence of complications was demonstrated. Two clinical factors appeared to be prognostic of the overall survival: the presence of multiple brain metastases and the presence of extracerebral metastases.

Entities:  

Mesh：

Year:  1993        PMID： 7681997     DOI： 10.1016/0167-8140(93)90091-l

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN： 0167-8140            Impact factor:   6.280


  19 in total

Review 1.  Management of brain metastasis: past lessons, modern management, and future considerations.

Authors:  Eugene Koay; Erik P Sulman
Journal:  Curr Oncol Rep       Date:  2012-02       Impact factor: 5.075

2.  Does overall treatment time impact on survival after whole-brain radiotherapy for brain metastases?

Authors:  C Nieder; N H Andratschke; O Spanne; H Geinitz; A L Grosu
Journal:  Clin Transl Oncol       Date:  2011-12       Impact factor: 3.405

3.  Decision making in palliative radiation therapy: reframing hope in caregivers and patients with brain metastases.

Authors:  Jacqueline Sze; Stephen Marisette; Diane Williams; Joyce Nyhof-Young; Dauna Crooks; Amna Husain; Andrea Bezjak; Rebecca K S Wong
Journal:  Support Care Cancer       Date:  2006-02-25       Impact factor: 3.603

Review 4.  Brain metastases: treatment options to improve outcomes.

Authors:  Phillip Davey
Journal:  CNS Drugs       Date:  2002       Impact factor: 5.749

Review 5.  The role of whole brain radiation therapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline.

Authors:  Laurie E Gaspar; Minesh P Mehta; Roy A Patchell; Stuart H Burri; Paula D Robinson; Rachel E Morris; Mario Ammirati; David W Andrews; Anthony L Asher; Charles S Cobbs; Douglas Kondziolka; Mark E Linskey; Jay S Loeffler; Michael McDermott; Tom Mikkelsen; Jeffrey J Olson; Nina A Paleologos; Timothy C Ryken; Steven N Kalkanis
Journal:  J Neurooncol       Date:  2009-12-04       Impact factor: 4.130

Review 6.  Radiotherapy for metastatic brain tumors.

Authors:  Yuta Shibamoto; Chikao Sugie; Hiromitsu Iwata
Journal:  Int J Clin Oncol       Date:  2009-08-25       Impact factor: 3.402

7.  Exploration of symptoms clusters within cancer patients with brain metastases using the Spitzer Quality of Life Index.

Authors:  Amanda Hird; Jennifer Wong; Liying Zhang; May Tsao; Elizabeth Barnes; Cyril Danjoux; Edward Chow
Journal:  Support Care Cancer       Date:  2009-05-31       Impact factor: 3.603

8.  CONCURRENT WHOLE BRAIN RADIOTHERAPY AND SHORT-COURSE CHLOROQUINE IN PATIENTS WITH BRAIN METASTASES: A PILOT TRIAL.

Authors:  Harriet Belding Eldredge; Albert Denittis; James B Duhadaway; Michael Chernick; Richard Metz; George C Prendergast
Journal:  J Radiat Oncol       Date:  2013-09-01

Review 9.  Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases.

Authors:  May N Tsao; Wei Xu; Rebecca Ks Wong; Nancy Lloyd; Normand Laperriere; Arjun Sahgal; Eileen Rakovitch; Edward Chow
Journal:  Cochrane Database Syst Rev       Date:  2018-01-25

10.  Quality of life in brain metastases radiation trials: a literature review.

Authors:  J Wong; A Hird; A Kirou-Mauro; J Napolskikh; E Chow
Journal:  Curr Oncol       Date:  2008-10       Impact factor: 3.677
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