Literature DB >> 7680768

Primary structure and functional expression of a mouse inward rectifier potassium channel.

Y Kubo1, T J Baldwin, Y N Jan, L Y Jan.   

Abstract

A complementary DNA encoding an inward rectifier K+ channel (IRK1) was isolated from a mouse macrophage cell line by expression cloning. This channel conducts inward K+ current below the K+ equilibrium potential but passes little outward K+ current. The IRK1 channel contains only two putative transmembrane segments per subunit and corresponds to the inner core structure of voltage-gated K+ channels. The IRK1 channel and an ATP-regulated K+ channel show extensive sequence similarity and constitute a new superfamily.

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Year:  1993        PMID： 7680768     DOI： 10.1038/362127a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  333 in total

1.  The inwardly rectifying K(+) channel subunit GIRK1 rescues the GIRK2 weaver phenotype.

Authors:  P Hou; S Yan; W Tang; D J Nelson
Journal:  J Neurosci       Date:  1999-10-01       Impact factor: 6.167

2.  Supralinear summation of synaptic inputs by an invertebrate neuron: dendritic gain is mediated by an "inward rectifier" K(+) current.

Authors:  R Wessel; W B Kristan; D Kleinfeld
Journal:  J Neurosci       Date:  1999-07-15       Impact factor: 6.167

3.  Differentiation of mammalian vestibular hair cells from conditionally immortal, postnatal supporting cells.

Authors:  P Lawlor; W Marcotti; M N Rivolta; C J Kros; M C Holley
Journal:  J Neurosci       Date:  1999-11-01       Impact factor: 6.167

4.  Effects of intra- and extracellular acidifications on single channel Kir2.3 currents.

Authors:  G Zhu; S Chanchevalap; N Cui; C Jiang
Journal:  J Physiol       Date:  1999-05-01       Impact factor: 5.182

5.  Kir2.1 encodes the inward rectifier potassium channel in rat arterial smooth muscle cells.

Authors:  K K Bradley; J H Jaggar; A D Bonev; T J Heppner; E R Flynn; M T Nelson; B Horowitz
Journal:  J Physiol       Date:  1999-03-15       Impact factor: 5.182

6.  Cardioselectivity of the sulphonylurea HMR 1098: studies on native and recombinant cardiac and pancreatic K(ATP) channels.

Authors:  Jocelyn E Manning Fox; Hussein D Kanji; Robert J French; Peter E Light
Journal:  Br J Pharmacol       Date:  2002-01       Impact factor: 8.739

7.  T-tubule localization of the inward-rectifier K(+) channel in mouse ventricular myocytes: a role in K(+) accumulation.

Authors:  R B Clark; A Tremblay; P Melnyk; B G Allen; W R Giles; C Fiset
Journal:  J Physiol       Date:  2001-12-15       Impact factor: 5.182

8.  Integration of Shaker-type K+ channel, KAT1, into the endoplasmic reticulum membrane: synergistic insertion of voltage-sensing segments, S3-S4, and independent insertion of pore-forming segments, S5-P-S6.

Authors:  Yoko Sato; Masao Sakaguchi; Shinobu Goshima; Tatsunosuke Nakamura; Nobuyuki Uozumi
Journal:  Proc Natl Acad Sci U S A       Date:  2001-12-26       Impact factor: 11.205

9.  Inward rectifier K(+) current under physiological cytoplasmic conditions in guinea-pig cardiac ventricular cells.

Authors:  Keiko Ishihara; Ding-Hong Yan; Shintaro Yamamoto; Tsuguhisa Ehara
Journal:  J Physiol       Date:  2002-05-01       Impact factor: 5.182

Review 10.  Controlling potassium channel activities: Interplay between the membrane and intracellular factors.

Authors:  B A Yi; D L Minor; Y F Lin; Y N Jan; L Y Jan
Journal:  Proc Natl Acad Sci U S A       Date:  2001-09-25       Impact factor: 11.205
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