| Literature DB >> 7680236 |
A Plebani1, A R Proserpio, D Guarneri, M Buscaglia, G Cattoretti.
Abstract
Peripheral blood lymphocytes from fetal, term and adult subjects were analyzed with a panel of B- and T-lymphoid differentiation markers. CD1c +ve and CD5 +ve B cell (IgM +ve) percentage in fetal, cord and adult blood decreased significantly. Fetal and cord blood contained less CD2+ and CD3+ T lymphocytes and a higher percentage of CD38 +ve cells than adult blood. The phenotypic changes occurring during perinatal age in humans relate to the changes in the functional activities of the B and T lymphoid subsets from fetal to postnatal age.Entities:
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Year: 1993 PMID: 7680236 DOI: 10.1159/000243901
Source DB: PubMed Journal: Biol Neonate ISSN: 0006-3126