| Literature DB >> 7680103 |
A K Giri1.
Abstract
Paracetamol and aspirin are the two most widely used analgesics available for human use without prescription in several parts of the world. Paracetamol has an antipyretic activity, and aspirin has both antipyretic and anti-inflammatory activities. Characterization of the mutagenicity and clastogenicity of these drugs is essential for their overall safety assessment. In the present review, an attempt is made to evaluate the genotoxic effects of these two widely used analgesics based on available literature.Entities:
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Year: 1993 PMID： 7680103 DOI： 10.1016/0165-1110(93)90011-b
Source DB: PubMed Journal: Mutat Res ISSN： 0027-5107 Impact factor: 2.433