Literature DB >> 7679836

Randomized trial of FK 506/prednisone vs FK 506/azathioprine/prednisone after renal transplantation: preliminary report.

R Shapiro1, M L Jordan, V P Scantlebury, J J Fung, C Jensen, C Vivas, J McCauley, W D Irish, S Mitchell, A J Demetris.   

Abstract

FK 506 was used as a primary immunosuppressive agent in 125 cases of renal transplantation in a randomized trial comparing FK 506/prednisone with FK 506/azathioprine/prednisone. With a mean follow-up of 5.5 +/- 2.5 months, there has been a 6-month actuarial patient survival of 99% and graft survival of 88%. There is no difference thus far between the two-drug and three-drug groups, although there may be less rejection and diabetes in the three-drug group. These results suggest that FK 506 is a useful immunosuppressive agent in kidney transplantation.

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Year:  1993        PMID： 7679836      PMCID： PMC2975489     

Source DB:  PubMed          Journal:  Transplant Proc        ISSN： 0041-1345            Impact factor:   1.066


  3 in total

1.  FK 506 in clinical kidney transplantation.

Authors:  R Shapiro; M Jordan; V Scantlebury; J Fung; C Jensen; A Tzakis; J McCauley; P Carroll; C Ricordi; A J Demetris
Journal:  Transplant Proc       Date:  1991-12       Impact factor: 1.066

2.  Kidney transplantation under FK 506 immunosuppression.

Authors:  R Shapiro; M Jordan; J Fung; J McCauley; J Johnston; Y Iwaki; A Tzakis; T Hakala; S Todo; T E Starzl
Journal:  Transplant Proc       Date:  1991-02       Impact factor: 1.066

3.  Kidney transplantation under FK 506.

Authors:  T E Starzl; J Fung; M Jordan; R Shapiro; A Tzakis; J McCauley; J Johnston; Y Iwaki; A Jain; M Alessiani
Journal:  JAMA       Date:  1990-07-04       Impact factor: 56.272
  3 in total
  16 in total

1.  Renal transplantation under FK 506 in African-Americans: early experience.

Authors:  J McCauley; R Shapiro; H Woods; V Scantlebury; W Irish; J McMichael; M Jordan; C Vivas; T E Starzl
Journal:  Transplant Proc       Date:  1993-08       Impact factor: 1.066

2.  Pediatric kidney transplantation at the University of Pittsburgh.

Authors:  V P Scantlebury; R Shapiro; A Tzakis; M L Jordan; C Vivas; D Ellis; N Gilboa; L Hopp; W Irish; S Mitchell
Journal:  Transplant Proc       Date:  1994-02       Impact factor: 1.066

3.  Outcome after steroid withdrawal in renal transplant patients receiving tacrolimus-based immunosuppression.

Authors:  R Shapiro; M L Jordan; V P Scantlebury; C Vivas; H A Gritsch; J McCauley; D McQuitty; P Randhawa; W Irish; J McMichael; T R Hakala; R L Simmons; J J Fung; T E Starzl
Journal:  Transplant Proc       Date:  1998-06       Impact factor: 1.066

4.  Tacrolimus in renal transplantation.

Authors:  R Shapiro; M L Jordan; V P Scantlebury; C Vivas; H A Gritsch; J McCauley; D Ellis; N Gilboa; S Lombardozzi-Lane; P Randhawa; A J Demetris; W Irish; T R Hakala; R L Simmons; J J Fung; T E Starzl
Journal:  Transplant Proc       Date:  1996-08       Impact factor: 1.066

5.  HLA and cross-reactive antigen group matching for cadaver kidney allocation.

Authors:  T E Starzl; M Eliasziw; D Gjertson; P I Terasaki; J J Fung; M Trucco; J Martell; J McMichael; V Scantlebury; R Shapiro; A Donner
Journal:  Transplantation       Date:  1997-10-15       Impact factor: 4.939

Review 6.  A risk-benefit assessment of tacrolimus in transplantation.

Authors:  M Winkler; U Christians
Journal:  Drug Saf       Date:  1995-05       Impact factor: 5.606

7.  Renal transplantation at the University of Pittsburgh: the impact of FK506.

Authors:  R Shapiro; M Jordan; V P Scantlebury; C Vivas; H A Gritsch; A S Rao; M Trucco; A Zeevi; A J Demetris; P Randhawa
Journal:  Clin Transpl       Date:  1994

Review 8.  Tacrolimus. A review of its pharmacology, and therapeutic potential in hepatic and renal transplantation.

Authors:  D H Peters; A Fitton; G L Plosker; D Faulds
Journal:  Drugs       Date:  1993-10       Impact factor: 9.546

Review 9.  The superiority of tacrolimus in renal transplant recipients -- the Pittsburgh experience.

Authors:  R Shapiro; M L Jordan; V P Scantlebury; C Vivas; H A Gritsch; R J Corry; F Egidi; J McCauley; D Ellis; N Gilboa
Journal:  Clin Transpl       Date:  1995

10.  A prospective, randomized trial to compare tacrolimus and prednisone with and without mycophenolate mofetil in patients undergoing renal transplantation: first report.

Authors:  R Shapiro; M L Jordan; V P Scantlebury; C Vivas; H A Gritsch; F A Casavilla; J McCauley; J R Johnston; P Randhawa; W Irish; T R Hakala; J J Fung; T E Starzl
Journal:  J Urol       Date:  1998-12       Impact factor: 7.450
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