Literature DB >> 7678976

A randomised phase II trial of epirubicin and 5-fluorouracil versus cisplatinum in the palliation of advanced and recurrent malignant tumour of the salivary glands.

A S Jones1, D E Phillips, J A Cook, T R Helliwell.   

Abstract

Sixteen patients with advanced and recurrent malignant salivary gland tumours were admitted to a randomised trial and the response assessed. Seven patients received Epirubicin/5-Fluorouracil and none of these patients responded. Nine patients received Cisplatinum and only one patient had a partial response. The trial suggests that chemotherapy has no place in the treatment of advanced salivary gland malignant tumours.

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Year:  1993        PMID： 7678976      PMCID： PMC1968228          DOI： 10.1038/bjc.1993.19

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  15 in total

1.  Chemotherapy for adenocystic carcinoma.

Authors:  I F Tannock; D J Sutherland
Journal:  Cancer       Date:  1980-08-01       Impact factor: 6.860

2.  Hydroxyurea in the treatment of neoplasms of the head and neck. A resurvey.

Authors:  G J Richards; R G Chambers
Journal:  Am J Surg       Date:  1973-10       Impact factor: 2.565

3.  Effects of chlorambucil (NSC-3088) in 374 patients with advanced cancer. Eastern Clinical Drug Evualuation Program.

Authors:  G E Moore; I D Bross; R Ausman; S Nadler; R Jones; N Slack; A A Rimm
Journal:  Cancer Chemother Rep       Date:  1968-10

4.  Adriamycin/cis-platinum/cyclophosphamide combination chemotherapy for advanced carcinoma of the parotid gland.

Authors:  D S Alberts; M R Manning; S W Coulthard; C F Koopmann; T S Herman
Journal:  Cancer       Date:  1981-02-15       Impact factor: 6.860

5.  Complete response of a metastatic adenoid cystic carcinoma of the parotid gland to chemotherapy.

Authors:  J L Skibba; J D Hurley; H V Ravelo
Journal:  Cancer       Date:  1981-06-01       Impact factor: 6.860

6.  Carcinoma of major salivary glands.

Authors:  H Shidnia; N B Hornback; R Hamaker; R Lingeman
Journal:  Cancer       Date:  1980-02-15       Impact factor: 6.860

Review 7.  Partial remission of advanced adenoid cystic carcinoma obtained with adriamycin: a case report with a review of the literature.

Authors:  R J Vermeer; H M Pinedo
Journal:  Cancer       Date:  1979-05       Impact factor: 6.860

8.  Reporting results of cancer treatment.

Authors:  A B Miller; B Hoogstraten; M Staquet; A Winkler
Journal:  Cancer       Date:  1981-01-01       Impact factor: 6.860

9.  Chemotherapy of malignant major salivary gland neoplasms: a 25-year review of M. D. Anderson Hospital experience.

Authors:  R Rentschler; M A Burgess; R Byers
Journal:  Cancer       Date:  1977-08       Impact factor: 6.860

10.  Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. analysis and examples.

Authors:  R Peto; M C Pike; P Armitage; N E Breslow; D R Cox; S V Howard; N Mantel; K McPherson; J Peto; P G Smith
Journal:  Br J Cancer       Date:  1977-01       Impact factor: 7.640
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  3 in total

Review 1.  Systemic therapy in the management of metastatic or advanced salivary gland cancers.

Authors:  Aymen Lagha; Nesrine Chraiet; Mouna Ayadi; Sarra Krimi; Bassem Allani; Hela Rifi; Henda Raies; Amel Mezlini
Journal:  Head Neck Oncol       Date:  2012-05-04

2.  P-values, survival analyses and phase II trials.

Authors:  P Fayers
Journal:  Br J Cancer       Date:  1994-06       Impact factor: 7.640

Review 3.  Activity of chemotherapy in the palliative treatment of salivary gland tumors: review of the literature.

Authors:  Sophia Rizk; Annie Robert; Annick Vandenhooft; Mario Airoldi; Gabriela Kornek; Jean-Pascal Machiels
Journal:  Eur Arch Otorhinolaryngol       Date:  2007-04-06       Impact factor: 3.236
  3 in total

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