Literature DB >> 7678017

Investigation of sera reactive to hepatitis C virus by second-generation enzyme immunoassay.

E H Frost1.   

Abstract

Hepatitis C virus antibodies were detected by a second-generation enzyme immunoassay and investigated with a second-generation recombinant immunoblot assay. Most sera with optical density values of > or = 2.0, particularly those with optical densities of > or = 2.0 after a further 10-fold dilution, were positive in the second-generation recombinant immunoblot assay. Repeat testing of hemodialysis patients revealed excellent reproducibility and increased sensitivity of the second-generation enzyme immunoassay.

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Year:  1993        PMID： 7678017      PMCID： PMC262645          DOI： 10.1128/jcm.31.1.163-164.1993

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  14 in total

1.  Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome.

Authors:  Q L Choo; G Kuo; A J Weiner; L R Overby; D W Bradley; M Houghton
Journal:  Science       Date:  1989-04-21       Impact factor: 47.728

2.  Early US experience with anti-HCV kit in blood donors.

Authors:  J E Menitove; W A Richards; M Destree
Journal:  Lancet       Date:  1990-07-28       Impact factor: 79.321

3.  Recombinant immunoblot assay for hepatitis C virus antibody as predictor of infectivity.

Authors:  F Ebeling; R Naukkarinen; J Leikola
Journal:  Lancet       Date:  1990-04-21       Impact factor: 79.321

4.  Enzyme immunoassay system for panel testing.

Authors:  J Donohue; M Bailey; R Gray; J Holen; T M Huang; J Keevan; C Mattimiro; C Putterman; A Stalder; J Defreese
Journal:  Clin Chem       Date:  1989-09       Impact factor: 8.327

5.  Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis.

Authors:  H J Alter; R H Purcell; J W Shih; J C Melpolder; M Houghton; Q L Choo; G Kuo
Journal:  N Engl J Med       Date:  1989-11-30       Impact factor: 91.245

6.  Confirmation of hepatitis C virus infection by new four-antigen recombinant immunoblot assay.

Authors:  C L Van der Poel; H T Cuypers; H W Reesink; A J Weiner; S Quan; R Di Nello; J J Van Boven; I Winkel; D Mulder-Folkerts; P J Exel-Oehlers
Journal:  Lancet       Date:  1991-02-09       Impact factor: 79.321

7.  Hepatitis C virus antibodies among risk groups in Spain.

Authors:  J I Esteban; R Esteban; L Viladomiu; J C López-Talavera; A González; J M Hernández; M Roget; V Vargas; J Genescà; M Buti
Journal:  Lancet       Date:  1989-08-05       Impact factor: 79.321

8.  Serological markers of posttransfusion hepatitis C viral infection.

Authors:  D S Vallari; B W Jett; H J Alter; L T Mimms; R Holzman; J W Shih
Journal:  J Clin Microbiol       Date:  1992-03       Impact factor: 5.948

9.  An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis.

Authors:  G Kuo; Q L Choo; H J Alter; G L Gitnick; A G Redeker; R H Purcell; T Miyamura; J L Dienstag; M J Alter; C E Stevens
Journal:  Science       Date:  1989-04-21       Impact factor: 47.728

10.  Prevalence of antibodies to hepatitis C virus among patients with cryptogenic chronic hepatitis and cirrhosis.

Authors:  L J Jeffers; F Hasan; M De Medina; R Reddy; T Parker; M Silva; L Mendez; E R Schiff; M Manns; M Houghton
Journal:  Hepatology       Date:  1992-02       Impact factor: 17.425
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