Literature DB >> 7677982

Results of surgery for malignant bowel obstruction in advanced, unresectable, recurrent colorectal cancer.

P W Lau1, T G Lorentz.   

Abstract

When conservative treatment fails in the management of patients with malignant bowel obstruction secondary to advanced, recurrent colorectal cancer, the attitude toward surgery is often less than enthusiastic because of the limited life expectancy. We report a retrospective review of 30 patients with unresectable intra-abdominal disease who underwent laparotomy for the relief of bowel obstruction. Normal bowel function was restored in 19 patients (63 percent). The failures included five patients (17 percent) who died as a result of surgical complications and six patients (20 percent) who despite the surgery had continuing obstruction. Postoperative complications occurred in eight patients (27 percent). The median survival was significantly improved in those who benefited from the operation (192 days vs. 26 days; P = 0.0001). Whether the obstruction occurred at one site or more than one site appeared not to influence the outcome of surgery. Obstruction recurred after a mean symptom-free interval of 120 days in eight of those relieved by the initial operation. Half of these patients responded to conservative treatment, and surgery was again beneficial in three of the remaining four. Our results justify a more positive approach toward this problem, and, when conservatism fails, laparotomy should be undertaken in those who are not terminally ill.

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Year:  1993        PMID: 7677982     DOI: 10.1007/bf02050303

Source DB:  PubMed          Journal:  Dis Colon Rectum        ISSN: 0012-3706            Impact factor:   4.585


  7 in total

1.  Venting direct percutaneous jejunostomy (DPEJ) for drainage of malignant bowel obstruction in patients operated on for gastric cancer.

Authors:  Giuseppe Piccinni; Anna Angrisano; Mario Testini; Domenico Merlicco; Michele Nacchiero
Journal:  Support Care Cancer       Date:  2005-02-15       Impact factor: 3.603

Review 2.  Surgery for the resolution of symptoms in malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer.

Authors:  Sarah E Cousins; Emma Tempest; David J Feuer
Journal:  Cochrane Database Syst Rev       Date:  2016-01-04

Review 3.  Endoscopic and surgical palliation of gastrointestinal tumors.

Authors:  M Hünerbein
Journal:  Support Care Cancer       Date:  2004-03       Impact factor: 3.603

4.  Small bowel obstruction following low anterior resection: the impact of diversion ileostomy.

Authors:  Jensen T C Poon; Wai-Lun Law; Kin-Wah Chu
Journal:  Langenbecks Arch Surg       Date:  2004-04-22       Impact factor: 3.445

Review 5.  Palliative surgery for malignant bowel obstruction from carcinomatosis: a systematic review.

Authors:  Terrah J Paul Olson; Carolyn Pinkerton; Karen J Brasel; Margaret L Schwarze
Journal:  JAMA Surg       Date:  2014-04       Impact factor: 14.766

6.  Emergency department patients with small bowel obstruction: What is the anticipated clinical course?

Authors:  Sarah E Frasure; Amy Hildreth; Sukhjit Takhar; Michael B Stone
Journal:  World J Emerg Med       Date:  2016

7.  Malignant bowel obstruction in advanced cancer patients: epidemiology, management, and factors influencing spontaneous resolution.

Authors:  Albert Tuca; Ernest Guell; Emilio Martinez-Losada; Nuria Codorniu
Journal:  Cancer Manag Res       Date:  2012-06-13       Impact factor: 3.989

  7 in total

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