Literature DB >> 7675536

Isolation of Fasciola hepatica haemoglobin.

S McGonigle1, J P Dalton.   

Abstract

A haemoprotein released in vitro by adult Fasciola hepatica was purified by gel filtration chromatography on Sephacryl S-200 and ion-exchange chromatography on DEAE-Sepharose. The molecule, with an apparent molecular weight of > 200 kDa, contains a haem group and has absorption spectra characteristics similar to heamoglobins. N-terminal amino acid sequence analysis revealed no similarity between the F. hepatica haemoglobin and other vertebrate or invertebrate haemoglobins. Antibodies to the haemoglobin molecule can be detected in the sera of F. hepatica-infected bovines as early as 1 week after infection.

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Year:  1995        PMID: 7675536     DOI: 10.1017/s0031182000064969

Source DB:  PubMed          Journal:  Parasitology        ISSN: 0031-1820            Impact factor:   3.234


  9 in total

1.  Delineating distinct heme-scavenging and -binding functions of domains in MF6p/helminth defense molecule (HDM) proteins from parasitic flatworms.

Authors:  Victoria Martínez-Sernández; Mercedes Mezo; Marta González-Warleta; María J Perteguer; Teresa Gárate; Fernanda Romarís; Florencio M Ubeira
Journal:  J Biol Chem       Date:  2017-03-27       Impact factor: 5.157

2.  Induction of protective immunity in cattle against infection with Fasciola hepatica by vaccination with cathepsin L proteinases and with hemoglobin.

Authors:  J P Dalton; S McGonigle; T P Rolph; S J Andrews
Journal:  Infect Immun       Date:  1996-12       Impact factor: 3.441

3.  The MF6p/FhHDM-1 major antigen secreted by the trematode parasite Fasciola hepatica is a heme-binding protein.

Authors:  Victoria Martínez-Sernández; Mercedes Mezo; Marta González-Warleta; María J Perteguer; Laura Muiño; Esteban Guitián; Teresa Gárate; Florencio M Ubeira
Journal:  J Biol Chem       Date:  2013-11-26       Impact factor: 5.157

4.  Molecular cloning and immunolocalization of the 17 kDa myoglobin of Clonorchis sinensis.

Authors:  Young-Bae Chung; Hyun-Jong Yang; Sung-Jong Hong; Shin-Yong Kang; Mejeong Lee; Tae Yun Kim; Min-Ho Choi; Jong-Yil Chai; Sung-Tae Hong
Journal:  Parasitol Res       Date:  2003-04-29       Impact factor: 2.289

5.  Serodiagnosis of fasciolosis by fast protein liquid chromatography-fractionated excretory/secretory antigens.

Authors:  Kobra Mokhtarian; Lame Akhlaghi; Ahmad Reza Meamar; Elham Razmjou; Kourosh Manouchehri Naeini; Samaneh Gholami; Masoomeh Najafi Samei; Reza Falak
Journal:  Parasitol Res       Date:  2016-04-30       Impact factor: 2.289

6.  The hemoglobins of the trematodes Fasciola hepatica and Paramphistomum epiclitum: a molecular biological, physico-chemical, kinetic, and vaccination study.

Authors:  Sylvia Dewilde; A Iulia Ioanitescu; Laurent Kiger; Kambiz Gilany; Michael C Marden; Sabine Van Doorslaer; Jozef Vercruysse; Alessandra Pesce; Marco Nardini; Martino Bolognesi; Luc Moens
Journal:  Protein Sci       Date:  2008-07-11       Impact factor: 6.725

7.  A family of helminth molecules that modulate innate cell responses via molecular mimicry of host antimicrobial peptides.

Authors:  Mark W Robinson; Sheila Donnelly; Andrew T Hutchinson; Joyce To; Nicole L Taylor; Raymond S Norton; Matthew A Perugini; John P Dalton
Journal:  PLoS Pathog       Date:  2011-05-12       Impact factor: 6.823

8.  High-quality reference genome of Fasciola gigantica: Insights into the genomic signatures of transposon-mediated evolution and specific parasitic adaption in tropical regions.

Authors:  Xier Luo; Kuiqing Cui; Zhiqiang Wang; Zhipeng Li; Zhengjiao Wu; Weiyi Huang; Xing-Quan Zhu; Jue Ruan; Weiyu Zhang; Qingyou Liu
Journal:  PLoS Negl Trop Dis       Date:  2021-10-05

9.  Sheep and Cattle Reservoirs in the Highest Human Fascioliasis Hyperendemic Area: Experimental Transmission Capacity, Field Epidemiology, and Control Within a One Health Initiative in Bolivia.

Authors:  Santiago Mas-Coma; Paola Buchon; Ilra R Funatsu; Rene Angles; Patricio Artigas; M Adela Valero; M Dolores Bargues
Journal:  Front Vet Sci       Date:  2020-10-27
  9 in total

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