| Literature DB >> 7674842 |
S Lahiri1, C M Habibullah, Q Ayesha, A A Khan, V K Srinivas, R Naithani.
Abstract
The present study aimed to evaluate the effect of UV-B irradiation on the functional integrity, and the metabolic and detoxifying capacity of isolated rat hepatocytes. Isolated rat hepatocytes were irradiated in various doses (400 Jm-2, 600 Jm-2, 800 Jm-2 and 1000 Jm-2). The cells were assayed for total lactate dehydrogenase, Na(+)-K(+)-ATPase, ornithine carbamyltransferase activity (OCT) and urea production capacity. Lactate dehydrogenase and Na(+)-K(+)-ATPase activity were significantly decreased in all four irradiated groups (P < 0.001), whereas viability, OCT and urea production capacity showed no alterations.Entities:
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Year: 1995 PMID： 7674842 DOI： 10.1111/j.1600-0676.1995.tb00662.x
Source DB: PubMed Journal: Liver ISSN： 0106-9543