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Literature DB >> 767353

Hypersecretion of LH and FSH by a pituitary adenoma.

Abstract

A 51-year-old man who had a pituitary adenoma that appeared to be hypersecreting LH and FSH is described. Not only were serum LH and FSH concentrations above the normal ranges, but the serum concentrations of testosterone, free testosterone, and dihydrotestosterone were also above normal. Serum LH and FSH concentration increased in response to synthetic thyrotropin-releasing hormone as well as to synthetic gonadotropin-releasing hormone. The elevated hormone concentrations decreased following an initial partial hypophysectomy and decreased further following repeat hypophysectomy.

Entities: Chemical Disease Gene Species

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Year: 1976 PMID： 767353 DOI： 10.1210/jcem-42-3-544

Source DB: PubMed Journal: J Clin Endocrinol Metab ISSN： 0021-972X Impact factor: 5.958

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Cited

10 in total

1. Premature ovarian failure.

Authors: R Jewelewicz; M Schwartz
Journal: Bull N Y Acad Med Date: 1986-04

Review 2. Medical therapy of gonadotropin-producing and nonfunctioning pituitary adenomas.

Authors: Mansur E Shomali; Laurence Katznelson
Journal: Pituitary Date: 2002 Impact factor: 4.107

3. Paradoxical release of LH under TRH dynamic test in patients suffering from "psychogenic" erective sexual impotency: lack of neuroradiological signs for hypophyseal lesions.

Authors: J J Legros; D Ferreira de Almeida; J Servais; P Chiodera; A Thibaut; P Franchimont
Journal: J Endocrinol Invest Date: 1983-04 Impact factor: 4.256

4. Follicle stimulating hormone-secreting pituitary adenoma: inappropriate secretion and effect of pulsatile luteinizing hormone releasing hormone analogue (buserelin) administration.

Authors: S Damjanović; D Micić; V Popović; M Petakov; A Kendereski; M Sumarac; D Manojlović; J Mićić
Journal: J Endocrinol Invest Date: 1991-04 Impact factor: 4.256

Review 5. Endocrine inactive and gonadotroph adenomas: diagnosis and management.

Authors: M Losa; P Mortini; R Barzaghi; A Franzin; M Giovanelli
Journal: J Neurooncol Date: 2001-09 Impact factor: 4.130

6. Gonadotroph adenomas of the human pituitary: sex-related fine-structural dichotomy. A histologic, immunocytochemical, and electron-microscopic study of 30 tumors.

Authors: E Horvath; K Kovacs
Journal: Am J Pathol Date: 1984-12 Impact factor: 4.307

Hypersecretion of LH and FSH by a pituitary adenoma.

1. Premature ovarian failure.

Review 2. Medical therapy of gonadotropin-producing and nonfunctioning pituitary adenomas.

3. Paradoxical release of LH under TRH dynamic test in patients suffering from "psychogenic" erective sexual impotency: lack of neuroradiological signs for hypophyseal lesions.

4. Follicle stimulating hormone-secreting pituitary adenoma: inappropriate secretion and effect of pulsatile luteinizing hormone releasing hormone analogue (buserelin) administration.

Review 5. Endocrine inactive and gonadotroph adenomas: diagnosis and management.

6. Gonadotroph adenomas of the human pituitary: sex-related fine-structural dichotomy. A histologic, immunocytochemical, and electron-microscopic study of 30 tumors.

7. Gonadotroph cell adenoma of the pituitary in a women with long-standing hypogonadism.

8. Functional classification of pituitary adenomas.

9. Pituitary adenomas secreting more than two hormones.

Review 10. Updating the Landscape for Functioning Gonadotroph Tumors.