BACKGROUND: The aim of this study was to provide the prevalence and sex-ratio of subtypes of migraine diagnosed by neurological interview according to the criteria of the International Headache Society. METHODS: In all, 3000 males and 1000 females aged 40 years were randomly selected from the Danish population. They received a mailed questionnaire regarding migraine. The questionnaire response rate was 87%. People with self-reported migraine and a random sample of those reporting no migraine were invited to a headache interview, and a physical and a neurological examination. Those not reacting to the invitation were interviewed by telephone. Participation at the interview was 87%. Kappa was 0.77 validating self-reported migraine in the questionnaire against the diagnosis of the clinical interview. RESULTS: Lifetime prevalences of migraine without aura, migraine with aura, migraine aura without headache, and migrainous disorder were 8%, 4%, 1% and 1% in males and 16%, 7%, 3% and 2% in females. Overall lifetime prevalence of any type of migraine was 18%; 12% in males and 24% in females. This is lower than the sum of the prevalences since migraine diagnoses are not mutually exclusive. The male:female ratios of migraine without aura, migraine with aura, migraine aura without headache, and migrainous disorder were approximately 1:2. CONCLUSIONS: Migraine is more prevalent than previously thought. There was a significant preponderance in females of all the subtypes of migraine except migrainous disorder.
BACKGROUND: The aim of this study was to provide the prevalence and sex-ratio of subtypes of migraine diagnosed by neurological interview according to the criteria of the International Headache Society. METHODS: In all, 3000 males and 1000 females aged 40 years were randomly selected from the Danish population. They received a mailed questionnaire regarding migraine. The questionnaire response rate was 87%. People with self-reported migraine and a random sample of those reporting no migraine were invited to a headache interview, and a physical and a neurological examination. Those not reacting to the invitation were interviewed by telephone. Participation at the interview was 87%. Kappa was 0.77 validating self-reported migraine in the questionnaire against the diagnosis of the clinical interview. RESULTS: Lifetime prevalences of migraine without aura, migraine with aura, migraine aura without headache, and migrainous disorder were 8%, 4%, 1% and 1% in males and 16%, 7%, 3% and 2% in females. Overall lifetime prevalence of any type of migraine was 18%; 12% in males and 24% in females. This is lower than the sum of the prevalences since migraine diagnoses are not mutually exclusive. The male:female ratios of migraine without aura, migraine with aura, migraine aura without headache, and migrainous disorder were approximately 1:2. CONCLUSIONS:Migraine is more prevalent than previously thought. There was a significant preponderance in females of all the subtypes of migraine except migrainous disorder.
Authors: V Anttila; M Kallela; G Oswell; M A Kaunisto; D R Nyholt; E Hamalainen; H Havanka; M Ilmavirta; J Terwilliger; E Sobel; L Peltonen; J Kaprio; M Farkkila; M Wessman; A Palotie Journal: Am J Hum Genet Date: 2006-05-10 Impact factor: 11.025
Authors: R A Ophoff; J DeYoung; S K Service; M Joosse; N A Caffo; L A Sandkuijl; G M Terwindt; J Haan; A M van den Maagdenberg; J Jen; R W Baloh; M L Barilla-LaBarca; N L Saccone; J P Atkinson; M D Ferrari; N B Freimer; R R Frants Journal: Am J Hum Genet Date: 2001-06-28 Impact factor: 11.025
Authors: Asgeir Björnsson; Grétar Gudmundsson; Einar Gudfinnsson; María Hrafnsdóttir; John Benedikz; Svanhildur Skúladóttir; Kristleifur Kristjánsson; Michael L Frigge; Augustine Kong; Kári Stefánsson; Jeffrey R Gulcher Journal: Am J Hum Genet Date: 2003-09-25 Impact factor: 11.025