BACKGROUND: Anterior segment findings in AIDS patients presenting with cytomegalovirus (CMV) retinitis have not been specifically addressed in the American literature. METHODS: Our study evaluated 21 AIDS patients with CMV retinitis. RESULTS: Nineteen (90%) of these patients exhibited corneal endothelial deposits concurrent with CMV retinitis. The endothelial deposits were microscopic, opaque, linear flecks arranged in a reticular-like fashion. Of 42 eyes evaluated, 32 (76%) demonstrated active CMV retinitis. Corneal endothelial deposits were noted in 26 (81%) of the 32 eyes with retinitis. These corneal endothelial deposits were absent in the eyes which did not have CMV retinitis. CONCLUSION: Meticulous examination of the retina of an HIV-positive or AIDS patient who presents with reticularly arranged, linear, flecked corneal endothelial deposits should be performed to ensure that the diagnosis of CMV retinitis can be ruled out.
BACKGROUND: Anterior segment findings in AIDSpatients presenting with cytomegalovirus (CMV) retinitis have not been specifically addressed in the American literature. METHODS: Our study evaluated 21 AIDSpatients with CMV retinitis. RESULTS: Nineteen (90%) of these patients exhibited corneal endothelial deposits concurrent with CMV retinitis. The endothelial deposits were microscopic, opaque, linear flecks arranged in a reticular-like fashion. Of 42 eyes evaluated, 32 (76%) demonstrated active CMV retinitis. Corneal endothelial deposits were noted in 26 (81%) of the 32 eyes with retinitis. These corneal endothelial deposits were absent in the eyes which did not have CMV retinitis. CONCLUSION: Meticulous examination of the retina of an HIV-positive or AIDSpatient who presents with reticularly arranged, linear, flecked corneal endothelial deposits should be performed to ensure that the diagnosis of CMV retinitis can be ruled out.
Authors: A G Palestine; M M Rodrigues; A M Macher; C C Chan; H C Lane; A S Fauci; H Masur; D Longo; C M Reichert; R Steis Journal: Ophthalmology Date: 1984-09 Impact factor: 12.079
Authors: J G Gross; S A Bozzette; W C Mathews; S A Spector; I S Abramson; J A McCutchan; T Mendez; D Munguia; W R Freeman Journal: Ophthalmology Date: 1990-05 Impact factor: 12.079
Authors: A H Friedman; J Orellana; W R Freeman; M H Luntz; M B Starr; M L Tapper; I Spigland; H Roterdam; R Mesa Tejada; S Braunhut; D Mildvan; U Mathur Journal: Br J Ophthalmol Date: 1983-06 Impact factor: 4.638