Literature DB >> 7672125

Ultraviolet B irradiation increases endothelin-1 and endothelin receptor expression in cultured human keratinocytes.

R Tsuboi1, C Sato, Y Oshita, H Hama, T Sakurai, K Goto, H Ogawa.   

Abstract

The effect of ultraviolet B (UVB) irradiation on endothelin-1 (ET-1) and ET receptor expression was examined using cultured normal human keratinocytes. Keratinocytes secreted ET-1 in the medium at a level of 2.1 pg/day/10(5) cells. UVB irradiation up to 10 mJ/cm2 increased ET-1 secretion 3-fold, and potentiated expression of mRNA for ET-1. Both ETA and ETB receptor mRNAs were detected in keratinocytes, and their expression was up-regulated by 5 mJ/cm2 UVB irradiation.

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Year:  1995        PMID： 7672125     DOI： 10.1016/0014-5793(95)00912-s

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  11 in total

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Review 4.  New perspectives on the endothelin axis in pain.

Authors:  Travis P Barr; Sarah Kam; Alla Khodorova; Jean-Pierre Montmayeur; Gary R Strichartz
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6.  UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling.

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7.  Effect of radiation on brain tissue endothelin-1 level and tumor development.

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Journal:  Asian J Neurosurg       Date:  2017 Apr-Jun

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Review 10.  Lifting the veil on the keratinocyte contribution to cutaneous nociception.

Authors:  Matthieu Talagas; Nicolas Lebonvallet; François Berthod; Laurent Misery
Journal:  Protein Cell       Date:  2020-01-06       Impact factor: 14.870
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